Acid-Base Balance during Renal Replacement Therapies
According to established evidence, correction of metabolic acidosis is mandatory in acutely uremic patients. Bicarbonate, the physiological buffer, has almost totally replaced acetate in dialysis and has partially replaced lactate as a reinfusion solution in convective therapies. Bicarbonate does not require metabolic conversion and does not cause any known side effects, except for metabolic alkalosis deriving from excessive administration; it is also very well tolerated in the clinical setting, not interfering with cardiovascular and respiratory functions.
KeywordsRenal Replacement Therapy Metabolic Acidosis Continuous Renal Replacement Therapy Metabolic Alkalosis Bicarbonate Concentration
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