Aspiration of Airway Dead Space: a New Method to Enhance CO2 Elimination

  • E. De Robertis
  • B. Jonson
  • R. Tufano
Conference paper


Mechanical ventilation is a life-saving therapeutic modality in the treatment of critical diseases such as the acute respiratory injury (ALI) and the acute respiratory distress syndrome (ARDS). However, it can contribute to the progression of pulmonary disease by generating a “ventilatory-induced lung injury” (VILI) [1, 2]. VILI may contribute to morbidity and mortality in ARDS with multiple mechanisms. Trauma resulting from high airway pressure and over-distension may lead to air leakage [3]. Repeated lung collapse and re-expansion leads to important shear forces [4].


Tidal Volume Acute Respiratory Distress Syndrome Dead Space Respir Crit Acute Respiratory Distress Syndrome Patient 


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Copyright information

© Springer-Verlag Italia 2002

Authors and Affiliations

  • E. De Robertis
    • 1
  • B. Jonson
    • 2
  • R. Tufano
    • 1
  1. 1.Department of Anaesthesia and Intensive CareNaples University “Federico II”NaplesItaly
  2. 2.Department of Clinical PhysiologyUniversity HospitalLundSweden

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