Changing Patterns of Prophylaxis and Treatment of Bacterial and Viral Intestinal Infections

  • Saurabh Mehandru
  • Edmund J. Bini
  • Douglas T. Dieterich


Intestinal infections are a significant cause of mor- bidity and mortality in patients with human immun- odeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). The introduc- tion of highly active antiretroviral therapy (HAART) has significantly improved survival in HIV-infected patients [1–4]. With HAART, it is now possible to reconstitute the immune system, even in patients with advanced AIDS. As a result of HAART-induced increases in CD4 lymphocyte counts and decreases in HIV viral loads, there has been a dramatic reduction in the incidence of opportunistic intestinal infections and chronic diarrhea in HIV-infected patients [5–9]. Furthermore, treatment with potent antiretroviral therapy has increased the response to pathogen-spe- cific and empiric antidiarrheal therapy, decreased the incidence of recurrent diarrhea, and improved long- term survival in these individuals [5].


Human Immunodeficiency Virus Infection Mycobacterium Avium Complex Yersinia Enterocolitica Cytomegalovirus Retinitis Oral Ganciclovir 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia 2003

Authors and Affiliations

  • Saurabh Mehandru
  • Edmund J. Bini
  • Douglas T. Dieterich

There are no affiliations available

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