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Bacteria

  • Kashi Nath Prasad
  • Jyotsna Agarwal

Abstract

The relative importance of bacterial infections as a significant cause of morbidity and mortality in patients infected with human immunodeficiency virus (HIV) has been increasingly recognized since prophylaxis against opportunistic pathogens has improved. In a chart review of 126 deaths in HIV-infected patients, bacterial infections were the most common cause accounting for immediate death in 30% of cases [1]. The gastrointestinal tract is a major target organ in HIV-infected patients and diarrhea is the most common gastrointestinal symptom. Diarrhea affects 30%–50% and up to 90% of patients with acquired immunodeficiency syndrome (AIDS) in developed and developing countries, respectively. Bacterial pathogens are causative agents in more than 20% of cases of diarrhea in AIDS patients [2]. In most cases, diarrhea may wax and wane in AIDS patients but is usually chronic and associated with significant morbidity, including wasting and cachexia. Specific pathogens can be identified by a thorough diagnostic evaluation in 44%–85% of patients with chronic diarrhea, and up to 10% of them have multiple concomitant organisms [2]. Although the organisms most commonly identified in AIDS patients with chronic diarrhea are opportunistic pathogens such as Cryptosporidium, Isospora, microsporidia, and Mycobacterium avium complex etc., the usual pathogens that also affect immunocompetent individuals, such as Salmonella, Campylobacter, and Shigella species and some other bacterial pathogens, are reported to be more frequently involved in HIV-positive patients. These infections are often more severe, recurrent, and associated with extraintestinal complications.

Keywords

Human Immunodeficiency Virus Human Immunodeficiency Virus Patient Shigella Species Alkaline Peptone Water Eosin Methylene Blue Agar 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Stein M, O’Sullivan P, Wachtel T, et al(1992) Causes of death in persons with human immunodeficiency virus infection. Am J Med 93:387–390PubMedCrossRefGoogle Scholar
  2. 2.
    Framm SR, Soave R (1997) Agents of diarrhea. Med Clin North Am 81:427–448PubMedCrossRefGoogle Scholar
  3. 3.
    Kovacs A, Leaf HL, Simberkoff (1997) Bacterial infections. Med Clin North Am 81:319–344PubMedCrossRefGoogle Scholar
  4. 4.
    Baron EJ, Peterson LR, Finegold SM (eds) (1994) Enterobacteriaceae. In: Bailey and Scott’s Diagnostic Microbiology, 9th edn. Mosby, St. Louis, pp 362–385Google Scholar
  5. 5.
    Popoff MY, Minor LL (1997) Antigenic formulas of the Salmonella serovars, 7th revision. WHO Collaborating Center for Reference and Research on Salmonella, Pasteur Institute, Paris, FranceGoogle Scholar
  6. 6.
    Popoff MY, Bockemuhl J, Hickman-Brenner FW (1997) Supplement 1996 (no. 40) to the Kauffmann-White scheme. Res Microbiol 148:811–814PubMedCrossRefGoogle Scholar
  7. 7.
    Nelson MR, Shanson DC, Hawkins DA, et al(1993) Salmonella, Campylobacter and Shigella in HIV seropositive patients. AIDS 7:900–901CrossRefGoogle Scholar
  8. 8.
    Germani Y, Minssart P, Vohito M, et al(1998) Etiologies of acute persistent and dysenteric diarrheas in adults in Bengui, Central African Republic, in relation to human immunodeficiency virus serostatus. Am J Trop Med Hyg 59:1008–1014PubMedGoogle Scholar
  9. 9.
    Santin M, Torres-Tortosa M, Redondo A, et al (1998) Other infections Streptococcus pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa, Salmonella spp., Campylobacter spp., Nocardia asteroides, Rhodococcus equi and Bartonella spp. Enferm Infecc Microbiol Clin 16 [Suppl]:61–66PubMedGoogle Scholar
  10. 10.
    Chaisson RE (1988) Infections due to encapsulated bacteria, Salmonella, Shigella and Campylobacter. Infect Dis Clin North Am 2:475–484PubMedGoogle Scholar
  11. 11.
    Brown M, Eykyn SJ (2000) Non-typhoidal Salmonella bacteremia without gastroenteritis: a marker of underlying immunosuppression. Review of cases at St. Thomas’ Hospital. J Infect 41:256–259PubMedCrossRefGoogle Scholar
  12. 12.
    Tacconelli E, Tumbarello M, Ventura G (1998) Risk factors, nutritional status and quality of life in HIV infected patients with enteric salmonellosis. Ital J Gastroenterol Hepatol 30:167–172PubMedGoogle Scholar
  13. 13.
    Reina J, Riera M, Hervas J (1993) Etiology of bacterial gastroenteritis in patients infected by the human immunodeficiency virus. Rev Clin Esp 193:428–430PubMedGoogle Scholar
  14. 14.
    Pithie AD, Malin AS, Robertson VJ (1993) Salmonella and Shigella bacteremia in Zimbabwe. Cent Afr J Med 39:110–112PubMedGoogle Scholar
  15. 15.
    Attia A, Huet C, Anglaret X, et al(2001) HIV-1 related morbidity in adults, Abidjan, Cote d’lvoire: A nidus for bacterial diseases. J Acquir Immune Defic Syndr 28:478–486PubMedGoogle Scholar
  16. 16.
    Metzler J, Nachamkin I (1988) Evaluation of a latex agglutination test for the detection of Salmonella and Shigella spp. by using broth enrichment. J Clin Microbiol 26:2501–2504PubMedGoogle Scholar
  17. 17.
    Old DC, Threlfell EJ (1998) Salmonella. In: Collier L, Balows A Sussman M (eds) Topley and Wilson’s microbiology and microbial infections, 9th edn., vol 2. Arnold, London, pp 969–997Google Scholar
  18. 18.
    Acheson DWK, Keusch GT (1995) Shigella and enteroinvasive Escherichia coli. In: Blaser MJ, Ravdin JI, Greenberg HB, Guerrant RL (eds) Infections of the gastrointestinal tract. Raven Press, New York, pp 763–784Google Scholar
  19. 19.
    Baer JT, Vugia DJ, Reingold AL, et al(1999) HIV infection as a risk factor for shigellosis. Emerg Infect Dis 5:820–823PubMedCrossRefGoogle Scholar
  20. 20.
    Kristjansson M, Viner B, Maslow JN (2000) Polymicrobial and recurrent bacteremia with Shigella in a patient with AIDS. Scand J Infect Dis 32:578CrossRefGoogle Scholar
  21. 21.
    Batchelor BI, Kimari JN, Brindle RJ (1996) Microbiology of HIV associated bacteremia and diarrhoea in adults from Nairobi, Kenya. Epidemiol Infect 117:139–44PubMedCrossRefGoogle Scholar
  22. 22.
    Olmos M, Molina C, Piskorz E (1996) Diarrhea and AIDS: more complex diagnostic techniques; better therapeutic results. Acta Gastroenterol Latinoam 26:91–100PubMedGoogle Scholar
  23. 23.
    Gzavava C, Chihota VN, Gangaidzo IT, et al(2001) Dysentery in patients with human immunodeficiency virus in Zimbabwe: an emerging role for Schistosoma mansoni and Escherichia coli O157? Ann Trop Med Parasitol 95:509–513CrossRefGoogle Scholar
  24. 24.
    Nataro JP, Kaper JB (1998) Diarrheagenic Escherichia coli. Clin Microbiol Rev 11:142–201PubMedGoogle Scholar
  25. 25.
    Wanke CA, Mayer H, Weber R, et al(1998) Enteroag-gregative Escherichia coli as a potential cause of diarrheal disease in adults infected with human immunodeficiency virus. J Infect Dis 178:185–190PubMedCrossRefGoogle Scholar
  26. 26.
    Wanke CA, Gerrior J, Blais V, et al(1998) Successful treatment of diarrhoeal disease associated with enteroaggregative Escherichia coli in adults infected with human immunodeficiency virus. J Infect Dis 178:1369–1372PubMedCrossRefGoogle Scholar
  27. 27.
    Dürrer P, Zbinden R, Fleisch F, et al(2000) Intestinal infection due to enteroaggregative Escherichia coli among human immunodeficiency virus infected persons. J Infect Dis 182:1540–1544PubMedCrossRefGoogle Scholar
  28. 28.
    Mathewson JJ, Jiang ZD, Zumla A, et al(1995) HEp-2 cell adherent Escherichia coli in patients with human immunodeficiency virus associated diarrhoea. J Infect Dis 17:1636–1639CrossRefGoogle Scholar
  29. 29.
    Orenstein JM, Kotler DP (1995) Diarrhoeagenic bacterial enteritis in acquired immune deficiency syndrome: a light and electron microscopy study of 52 cases. Hum Pathol 26:481–492PubMedCrossRefGoogle Scholar
  30. 30.
    Cravioto A, Gross RJ, Scotland SM, et al(1979) An adhesive factor found in strains of Escherichia coli belonging to the traditional infantile enteropathogenic serotypes. Curr Microbiol 3:95–99CrossRefGoogle Scholar
  31. 31.
    Kopecko DJ (1994) Experimental keratoconjunctivitis (Sereny) assay. In: Clark VL, Bavoil PM (eds) Bacterial pathogenesis, part A. Academic Press, San Diego, PP 39–46Google Scholar
  32. 32.
    Menard R, Sansonetti PJ (1994) Shigella flexneri: isolation of non-invasive mutants of Gram-negative pathogens. Methods Enzymol 236:493–509PubMedCrossRefGoogle Scholar
  33. 33.
    Nachamkin I (1999) Campylobacter and Arcobacter. In: Murray PR, Barron EJ, Pfaller MA, Tenover FC, Yolken RH (eds) Manual of Clinical Microbiology. American Society for Microbiology, Washington DC, pp 716–726Google Scholar
  34. 34.
    Blaser MJ (1995) Campylobacter and related species. In: Mandell GL, Bennet JE, Dolin R (eds) Principles and practice of infectious diseases. Churchill Livingstone, New York, pp 1948–1956Google Scholar
  35. 35.
    Molina J, Casin I, Hausfater P, et al(1995) Campylobacter infections in HIV infected patients: clinical and bacteriological features. AIDS 9:881–885PubMedCrossRefGoogle Scholar
  36. 36.
    Sniders F, Kuijper EJ, De Wever B, et al(1997) Prevalence of Campylobacter-associated diarrhoea among patients infected with human immunodeficiency virus. Clin Infect Dis 24:1107–1113CrossRefGoogle Scholar
  37. 37.
    Tee W, Mijch A (1998) Campylobacter jejuni bacteremia in human immunodeficiency virus (HIV-infected and non-HIV-infected patients: comparison of clinical features and review. Clin Infect Dis 26:91–96PubMedCrossRefGoogle Scholar
  38. 38.
    Prasad KN, Nag VL, Ayyagari A, et al(2000) Identification of enteric pathogens in HIV-positive patients with diarrhoea in northern India. J Health Popul Nutr 18:23–26PubMedGoogle Scholar
  39. 39.
    Jenkin GA, Tee W (1998) Campylobacter upsaliensis-associated diarrhoea in human immunodeficiency virus-infected patients. Clin Infect Dis 27:816–821PubMedCrossRefGoogle Scholar
  40. 40.
    Leyes M, Vara F, Reina J, et al(1994) Campylobacter enteritis in patients with human immunodeficiency virus infection. Enferm Infecc Microbiol Clin 12:332–336PubMedGoogle Scholar
  41. 41.
    Fernandez-Martin JI, Dronda F, Chaves F, et al(1996) Campylobacter jejuni infections in a prison population coinfected with the human immunodeficiency virus. Rev Clin Esp 196:16–20PubMedGoogle Scholar
  42. 42.
    Mishu B, Blaser MJ (1994) Campylobacter jejuni, human immunodeficiency virus, and Guillain-Barre syndrome. J Infect Dis 169:1177PubMedCrossRefGoogle Scholar
  43. 43.
    Wang WLL, Reller LB, Smallwood B, et al(1983) Evaluation of transport media for Campylobacter jejuni in human fecal specimens. J Clin Microbiol 18:803–807PubMedGoogle Scholar
  44. 44.
    Park CH, Hixon DL, Polhemus AS, et al(1983) A rapid diagnosis of Campylobacter enteritis by direct smear examination. Am J Clin Path 80:388–390PubMedGoogle Scholar
  45. 45.
    Nachamkin I, Engberg J, Aarestup FM (2000) Diagnosis and antimicrobial susceptibility of Campylobacter species. In: Nachamkin I, Blaser MJ (eds) Campylobacter, 2nd edn. American Society for Microbiology, Washington DC, pp 45–66Google Scholar
  46. 46.
    Piersimoni C, Bornigia S, Curzi L, et al(1995) Comparison of two selective media and a membrane filtration technique for isolation of Campylobacter species from diarrhoeal stool. Eur J Clin Microbiol Infect Dis 14:539–542PubMedCrossRefGoogle Scholar
  47. 47.
    Kasten MJ, Allerberger F, Anhalt JP (1991) Campylobacter bacteremia: clinical experience with three blood culture systems at Mayo Clinic 1984-1990. Infection 19:88–90PubMedCrossRefGoogle Scholar
  48. 48.
    On SLW (1996). Identification methods for Campylobacters, Helicobacters and related organisms. Clin Microbiol Rev 9:405–422PubMedGoogle Scholar
  49. 49.
    Slater ER, Owen RJ (1997) Restriction fragment length polymorphism analysis shows that the hippuricase gene of Campylobacter jejuni is highly conserved. Lett Appl Microbiol 25:274–278PubMedCrossRefGoogle Scholar
  50. 50.
    Nachamkin I, Barbagallo S (1990) Culture confirmation of Campylobacter species by latex agglutination. J Clin Microbiol 28:817–818PubMedGoogle Scholar
  51. 51.
    Popovic-Uroic T, Patton CM, Wachsmuth IK, et al (1991) Evaluation of an oligonucleotide probe for identification of Campylobacter species. Lab Med 22:533–539Google Scholar
  52. 52.
    Lawson AJ, Logan JMJ, ONeill GL, et al(1999) Largescale survey of Campylobacter species in human gastroenteritis by PCR and PCR-enzyme-linked immunosorbent assay. J Clin Microbiol 37:3860–3864PubMedGoogle Scholar
  53. 53.
    Lior H, Woodward DL, Edgar JA, et al(1982). Serotyping of Campylobacter jejuni by slide agglutination based on heat-labile antigenic factors. J Clin Microbiol 15:761–768PubMedGoogle Scholar
  54. 54.
    Penner JL, Hennessy JN (1980) Passive hemagglutination technique for serotyping Campylobacter fetus subsp. jejuni on the basis of heat-stable antigens. J Clin Microbiol 12:732–737PubMedGoogle Scholar
  55. 55.
    Patton CM, Wachsmuth IK (1992) Typing schemes: are current methods useful? In: Nachamkin I, Blaser MJ, Tompkins LS (eds) Campylobacter jejuni: current status and future trends. American Society for Microbiology, Washington DC, pp 110–128Google Scholar
  56. 56.
    Lyerly DM, Krivan HC, Wlikins TD (1988) Clostridium difficile: its disease and toxin. Clin Microbiol Rev 1:1–18PubMedGoogle Scholar
  57. 57.
    Allen SD, Emery CL, Siders JA (1999) Clostridium. In: Murray PR, Barron EJ, Pfaller MA, Tenover FD, Yolken RH (eds) Manual of clinical microbiology, 7th edn. American Society for Microbiology Press, Washington DC, pp 654–689Google Scholar
  58. 58.
    Borriello SP, Barclay FE, Welch AR, et al(1985) Epidemiology of diarrhoea caused by enterotoxigenic Clostridium perfringens. J Med Microbiol 20:363–372PubMedCrossRefGoogle Scholar
  59. 59.
    Gordin F, Gilbert C, Schmidt ME (1994) Clostridium difficile colitis associated with trimethoprim-sulfamethoxazole given as prophylaxis for Pneumocystis carinii pneumonia. Am J Med 96:84CrossRefGoogle Scholar
  60. 60.
    Tumbarello M, Taccinolli E, Leone F, et al(1995) Clostridium difficile-associated diarrhea in patients with human immunodeficiency virus infection: a case control study. Eur J Gastroenterol Hepatol 7:259–263PubMedGoogle Scholar
  61. 61.
    Barbut F, Meynard JL, Guiguet M, et al(1997) Clostridium difficile-associated diarrhea in HIV infected patients: epidemiology and risk factors. J Acquir Immune Defic Syndr Hum Retrovirol 16:176–181PubMedCrossRefGoogle Scholar
  62. 62.
    Wongwanich S, Ramsiri S, Kusum M, et al(2000) Clostridium difficile infection in HIV positive patients. Southeast Asian J Trop Med Public Health 31:537–539PubMedGoogle Scholar
  63. 63.
    Zulu I, Kelly P, Mwansa, et al(2000) Contrasting incidence of Clostridium difficile and other enteropathogens in AIDS in London and Lusaka. Trans Roy Soc Trop Med Hyg 94:167–168PubMedCrossRefGoogle Scholar
  64. 64.
    Mody LR, Smith SM, Dever LL (2001) Clostridium difficile-associated+diarrhoea in a VA medical center: clustering of cases, association with antibiotic usage, and impact on HIV infected patients. Infect Control Hosp Epidemiol 22:42–45PubMedCrossRefGoogle Scholar
  65. 65.
    Alonso R, Gros S, Pelaez T, et al(2001) Molecular analysis of relapse vs re-infection in HIV-positive patients suffering from recurrent Clostridium difficile associated diarrhea. J Hosp Infect 48:86–92PubMedCrossRefGoogle Scholar
  66. 66.
    Lu SS, Schwartz JM, Simon DM, et al (1994) Clostridium difficile-associated diarrhea in patients with HIV positivity and AIDS: a prospective controlled study. Am J Gastroenterol 89:1226–1229PubMedGoogle Scholar
  67. 67.
    Cozart JC, Kalangi SS, Clench MH, et al(1993) Clostridium difficile diarrhea in patients with AIDS versus non AIDS controls. Methods of treatment and clinical response to treatment. J Clin Gastroenterol 16:192–194PubMedCrossRefGoogle Scholar
  68. 68.
    Beaugerie L, Ngo Y, Goujard F, et al(1994) Etiology and management of toxic megacolon in patients with human immunodeficiency virus infection. Gastroenterology 107:858–863PubMedCrossRefGoogle Scholar
  69. 69.
    Stubbs SLJ, Brazier JS, O’Neill GL, et al(1999) PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes. J Clin Microbiol 37:461–463PubMedGoogle Scholar
  70. 70.
    Tison DL (1999) Vibrio. In: Murray PR, Barron EJ, Pfaller MA, Tenover FD, Yolken RH (eds) Manual of clinical microbiology, 7th edn. American Society for Microbiology Press, Washington DC, pp 497–506Google Scholar
  71. 71.
    Laughon BE, Druckman DA, Vermon A, et al(1988) Prevalence of enteric pathogens in homosexual men with and without acquired immunodeficiency syn drome. Gastroenterology 94:984–993PubMedGoogle Scholar
  72. 72.
    Chin KP, Lowe MA, Tong MJ, et al(1987) Vibrio vulnificus infection after raw oyster ingestion in a patient with liver disease and acquired immunodeficiency syndrome-related complex. Gastroenterology 92:796–799PubMedGoogle Scholar
  73. 73.
    Farina C, Luzzi I, Lorenzi N (1999) Vibrio cholerae O2 sepsis in a patient with AIDS. Eur J Clin Microbiol Infect Dis 18:203–205PubMedCrossRefGoogle Scholar
  74. 74.
    Hodge TW Jr, Levy CS, Smith MA (1995) Diarrhoea associated with Vibrio fluvialis infection in a patient with AIDS. Clin Infect Dis 21:237–238PubMedCrossRefGoogle Scholar
  75. 75.
    Blanche P, Sicard D, Sevali Garcia J, et al(1994) Septicemia due to non-O1 Vibrio cholerae in a patient with AIDS. Clin Infect Dis 19:813PubMedCrossRefGoogle Scholar
  76. 76.
    Altwegg M (1999) Aeromonas and Plesiomonas. In: Murray PR, Barron EJ, Pfaller MA, Tenover FD, Yolken RH (eds) Manual of clinical microbiology, 7th edn. American Society for Microbiology Press, Washington DC, pp 507–516Google Scholar
  77. 77.
    Liao WC, Cappell MS (1989) Treatment with ciprofloxacin of Aeromonas hydrophila associated colitis in a male with antibodies to the human immunodeficiency virus. J Clin Gastroenterol 11:552–554PubMedCrossRefGoogle Scholar
  78. 78.
    Roberts IM, Parenti DM, Albert MB (1987) Aeromonas hydrophila associated colitis in a male homosexual. Arch Intern Med 147:1502–1503PubMedCrossRefGoogle Scholar
  79. 79.
    Thomsen RN, Kristianse MM (2001) Three case of bacteraemia caused by Aeromonas veronii biovar sobria. Scand J Infect Dis 33:718–719PubMedCrossRefGoogle Scholar
  80. 80.
    Holmberg SD, Wachsmuth IK, Hickman-Brenner FW, et al (1986) Plesiomonas enteric infctions in the United States. Ann Intern Med 105:690–694PubMedGoogle Scholar
  81. 81.
    Brenden RA, Miller MA, Janda JM (1988) Clinical disease spectrum and pathogenic factors associated with Plesiomonas shigelloides infections in humans. Rev Infect Dis 10:303–316PubMedCrossRefGoogle Scholar
  82. 82.
    Rolston KV, Zandvliet SE, Rodriguez S, et al(1991) Spectrum of Aeromonas and Plesiomonas infections in patients with cancer and AIDS. Experientia 47:437–439PubMedGoogle Scholar
  83. 83.
    Ahmad M, Aggarwal M, Ahmed A (1998) Bloody diarrhoea caused by Plesiomonas shigelloides proctitis in a human immunodeficiency virus-infected patient. Clin Infect Dis 27:657PubMedCrossRefGoogle Scholar
  84. 84.
    Suthienkul 0, Aiumlaor P, Siripanichgon K, et al (2001) Bacterial causes of AIDS associated diarrhoea in Thailand. Southeast Asian J Trop Med Public Health 32:158–170PubMedGoogle Scholar
  85. 85.
    Wexner SD (1990) Sexually transmitted diseases of colon, rectum, and anus. The challenge of the nineties. Dis Colon Rectum 33:1048–1062PubMedCrossRefGoogle Scholar
  86. 86.
    Mora M, Rivas A, Dib J (1989) Chlamydial proctitis in homosexual men. GEN 43:295–297Google Scholar
  87. 87.
    Rompalo AM (1999) Diagnosis and treatment of sexually acquired proctis and proctocolitis: an update. Clin Infect Dis 28[Suppl 1]:S84-90Google Scholar
  88. 88.
    Cohen J, West AB, Bini EJ (2001) Infectious diarrhea in human immunodeficiency virus. Gastroenterol Clin North Am 30:637–664PubMedCrossRefGoogle Scholar
  89. 89.
    Lo TC, Heading RC, Gilmour HM (1994) Intestinal spirochetosis. Postgrad Med J 70:134PubMedCrossRefGoogle Scholar
  90. 90.
    Nielsen RH, Orholm M, Pederson JO, et al(1983) Colorectal spirochetosis: clinical significance of the infestation. Gastroenterology 85:62PubMedGoogle Scholar
  91. 91.
    Kasbohrer A, Gelderblom HR, Arasteh K, et al(1990) Intestinal spirochetosis in HIV infection: prevalence, isolation and morphology. Dtsch Med Wochenschr 115:1499–1506PubMedCrossRefGoogle Scholar
  92. 92.
    Lafeuillade A, Delbeke E, Benderitter T, et al(1990) Intestinal spirochetosis in homosexuals infected with HIV, 3 cases. Ann Med Interne 141:464–467Google Scholar
  93. 93.
    Mikosza AS, Hampson DJ (2001) Human intestinal spirochetosis: Brachyspira aalborgi and/ or Brachyspira pilosicoli. Animal Health Res Rev 2:101–110Google Scholar
  94. 94.
    Fish D, Danziger CH (1993) Neglected pathogens: bacterial infections in persons with human immunodeficiency virus infection. Pharmacotherapy 13:543–563PubMedGoogle Scholar
  95. 95.
    Berenguer J, Solera J, Diaz MD, et al(1991) Listeriosis in patients infected with human immunodeficiency virus infection. Rev Infect Dis 13:115PubMedCrossRefGoogle Scholar
  96. 96.
    Atlas RM, Parks LC (eds) (1993) Handbook of microbiological media. CRC Press, Boca RatonGoogle Scholar

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Authors and Affiliations

  • Kashi Nath Prasad
  • Jyotsna Agarwal

There are no affiliations available

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