A Review of the SCD-HEFT, COMPANION, and CARE-HF Trials
The past 10 years have provided a series of well-designed clinical trials to study the effect of the implantable cardioverter defibrillator (ICD) in patients at high risk of sudden death. These studies have been carried out on both sides of the Atlantic. Patient populations have been recruited both from post-event populations and from pre-event populations judged to be at high enough risk to warrant prophylactic ICD implantation. The results of both categories of trial have been remarkably similar. Interestingly, the primary prevention studies were both initiated first and have shown more positive impact of ICD implantation on survival than the secondary prevention trials.
KeywordsImplantable Cardioverter Defibrillator Implantable Cardioverter Defibrillator Therapy Implantable Cardioverter Defibrillator Implantation Multicenter Automatic Defibrillator Implantation Trial Conventional Therapy Group
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