Recent and Ongoing Trials on Device Therapy of Atrial Fibrillation

  • P. Delise
Conference paper


Atrial fibrillation is a complex arrhythmia from both an electrophysiologic and a clinical point of view. As to its electrophysiologic mechanism, three main factors are at work: triggers, initiators, and perpetuators [1,2]. Several triggers have been identified [3-6]: supraventricular reentry tachycardias, atrial extrasystoles, and, more recently, pulmonary vein foci. Possible initiators are Bachmann’s bundle [7] and other critical atrial areas. Finally, the perpetuators are atrial electrophysiologic and anatomic alterations (atrial dilatation, fibrosis, and/or fatty degeneration) which represent the substrate of sustained atrial fibrillation [8,9].


Atrial Fibrillation Paroxysmal Atrial Fibrillation Atrial Tachycardia Atrial Pace Chronic Atrial Fibrillation 
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Copyright information

© Springer-Verlag Italia 2003

Authors and Affiliations

  • P. Delise
    • 1
  1. 1.Operative Unit of CardiologyHospital of ConeglianoTrevisoItaly

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