Amiodarone in the Treatment of Atrial Fibrillation: New Perspectives from Clinical Trials
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and both its incidence and the burden it lays on the health system are steadily increasing, primarily because of the increase in the elderly proportion of the population [1-3]. Among the diverse pharmacological agents potentially useful in restoring and maintaining sinus rhythm, amiodarone is characterized by both a multiplicity of sites of action and high efficacy. Several studies have supported the use of this compound . Trials evaluating intravenous use of amiodarone have recently been reviewed in detail . The present paper will briefly evaluate a small number of recent clinical studies supporting the use of oral amiodarone in preventing recurrent episodes of AF in the general population and in selected clinical settings.
KeywordsAtrial Fibrillation Sinus Rhythm Open Heart Surgery Atrial Fibrillation Recurrence Postoperative Atrial Fibrillation
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