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Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance pp 39–45Cite as

Physiology and Pharmacology of Somatostatin and Its Receptors

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Abstract

Somatostatin is an “old” neuropeptide, discovered 30 years ago as a hypothalamic neurohormone for its ability to inhibit growth hormone secretion (Brazeau et al, 1972). Later, it was found to be widely distributed in other brain regions, in which it fulfills a neuromodulatory role. It is also located in several organs of the gastrointestinal tract, where it can act as a paracrine factor or as a true circulating factor (Fig. 1).

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Authors
  1. J. Epelbaum
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Editors and Affiliations

  1. Department of Pharmacology, University of Milan, Milan, Italy

    Eugenio E. Müller

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© 2003 Springer-Verlag Italia

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Epelbaum, J. (2003). Physiology and Pharmacology of Somatostatin and Its Receptors. In: Müller, E.E. (eds) Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance. Springer, Milano. https://doi.org/10.1007/978-88-470-2085-6_4

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  • DOI: https://doi.org/10.1007/978-88-470-2085-6_4

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-2170-9

  • Online ISBN: 978-88-470-2085-6

  • eBook Packages: Springer Book Archive

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