Hormonal Treatments of Endocrine-Dependent Tumors: Preclinical Aspects
Breast and prostate carcinomas are the most frequently diagnosed diseases in the group of the so-called endocrine-dependent tumors. These diseases are given this name because their development and maintenance, and in several instances their progression, are sustained by the presence of gonadal hormones in the bloodstream, namely estrogens in females and androgens, particularly testosterone, the main testicular androgen, in males.
KeywordsBreast Cancer Prostate Cancer Androgen Receptor Aromatase Inhibitor GnRH Agonist
Unable to display preview. Download preview PDF.
- Bologna M., et al. (1992). Anti-androgens and 5alpha-reductase inhibition of the proliferation rate in PC3 and DU145 human prostatic cancer cell line. Curr Ther Res, 51,799–813.Google Scholar