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Excerpta Anestesiologica pp 99–113Cite as

L’acidosi ipercapnica nella ventilazione artificiale protettiva: compromesso tollerato o ulteriore fattore di protezione?

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Come acutamente faceva notare Laffey dieci anni fa [1], siamo tutti abituati a considerare utili per i pazienti critici i range di normalità comunemente accettati per i sani, ma questo tipo di strategia non è certamente fondato sulla realtà dei fatti. Per esempio, somministrando ai neonati prematuri O2 per raggiungere valori “normali” di PaO2 abbiamo contribuito alla produzione delle retinopatie e delle displasie broncopolmonari; trasfondendo i pazienti critici sino a raggiungere valori normali di Htc abbiamo aumentato la mortalità; avendo come obiettivo i valori pressori normali nei politraumatizzati abbiamo ridotto la loro possibilità di sopravvivenza. Non possiamo quindi aprioristicamente escludere che, tenendo la PaCO2 a valori elevati nei pazienti critici (o addirittura tenendola a valori più bassi del normale), si faccia un danno.

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  1. Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italia

    Biagio Allaria (Past Director del Dipartimento del paziente critico)

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  1. Biagio Allaria
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  1. Dipartimento del paziente critico, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italia

    Biagio Allaria (Past Director) (Past Director)

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Allaria, B. (2011). L’acidosi ipercapnica nella ventilazione artificiale protettiva: compromesso tollerato o ulteriore fattore di protezione?. In: Allaria, B. (eds) Excerpta Anestesiologica. Springer, Milano. https://doi.org/10.1007/978-88-470-2023-8_7

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  • DOI: https://doi.org/10.1007/978-88-470-2023-8_7

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  • Online ISBN: 978-88-470-2023-8

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