Source control is defined as all those physical measures necessary to eradicate a focus of infection as well as to control factors that maintain infection, promote microbial growth or impair host antimicrobial defences . Sepsis is defined as infection plus systemic manifestations of infection. Severe sepsis is defined as sepsis plus sepsis-induced organ dysfunction or tissue hypoperfusion [2, 3]. The term source control was first used in the early twentieth century but regained attention over the past 10 years when a panel of experts was asked to provide guidelines for treating severe sepsis and septic shock during the Surviving Sepsis Campaign project. The campaign was promoted by the European Society of Intensive Care Medicine (ESICM), the International Sepsis Forum (ISF) and the Society of Critical Care Medicine (SCCM) to increase awareness of and improve outcomes in severe sepsis . The last updated guidelines were published in 2008 . Recently, the campaign provided “bundles” to help improve guideline outcomes. Bundles help to simplify the complex processes of a septic patient’s care. A bundle is a simple principle of care resulting from evidence-based practice guidelines that, when implemented as a group, have a significant effect on outcomes beyond implementing the individual elements alone. Each hospital can elaborate a sepsis protocol, but it must meet the standards created by the bundle .
KeywordsSevere Sepsis Source Control Percutaneous Cholecystostomy Temporary Abdominal Closure Definitive Measure
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