Therapeutic Strategies in Unresectable Colorectal Liver Metastases

  • Alessandro Ferrero


The majority of patients with colorectal liver metastases presents with unresectable disease at diagnosis, because of the size, location, or extent of the tumor. While chemotherapy remains the first option for these patients, only multimodal management can increase the resectability rates. When patients cannot be safely operated on because the future liver remnant after the scheduled hepatectomy would be too small, portal vein occlusion is a safe procedure to decrease the risk of postoperative liver failure. Two-stage hepatectomy and associated interstitial treatments are effective strategies in case of multiple bilateral metastases.


Portal Vein Hepatic Resection Colorectal Liver Metastasis Portal Vein Embolization Future Liver Remnant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia 2011

Authors and Affiliations

  • Alessandro Ferrero
    • 1
  1. 1.Division of Hepato-Bilio-Pancreatic and Digestive SurgeryMauriziano “Umberto I” HospitalTurinItaly

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