Re-resection: Indications and Results

  • Andrea Muratore


Intrahepatic recurrence after curative liver resection is a common event. In the last 15 years, the rate of re-resection of a liver recurrence has progressively increased such that up to 20% of patients with an intrahepatic recurrence are now expected to undergo re-resection. Although re-resection is technically more demanding, mortality/morbidity and long-term survival rates are similar to those reported for initial liver resection. The major indication for re-resection is the technical feasibility of a curative procedure.


Liver Resection Hepatic Resection Colorectal Liver Metastasis Colorectal Metastasis Intrahepatic Recurrence 
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  1. 1.
    Capussotti L, Muratore A, Mulas M et al (2006) Neoadjuvant chemotherapy and resection for initially irresectable colorectal liver metastases. Br J Surg 93:1001–1006CrossRefPubMedGoogle Scholar
  2. 2.
    de Jong MC, Pulitano C, Ribero D et al (2009) Rates and patterns of recurrence following curative intent surgery for colorectal liver metastasis. An international multi-institutional analysis of 1669 patients. Ann Surg 250:440–448PubMedGoogle Scholar
  3. 3.
    Huguet C, Boba S, Nordlinger B et al (1990) Repaet hepatic resection for primary and metastatic carcinoma of the liver. Surgery Gynecol & Obstetrics 171:398–402Google Scholar
  4. 4.
    Fortner JG. (1988) Recurrence of colorectal cancer after hepatic resection. Am J Surg 155:378–382CrossRefPubMedGoogle Scholar
  5. 5.
    Nordlinger B, Vaillant JC, Guiguet M et al (1994) Survival benefit of repeat liver resections for recurrent colorectal metastases: 143 cases. J Clin Oncol 12:1491–1496PubMedGoogle Scholar
  6. 6.
    Fernandez-Trigo V, Shamsa F et al (1995) Repeat liver resection for colorectal metastasis. Surgery 117:296–304CrossRefPubMedGoogle Scholar
  7. 7.
    Muratore A, Polastri R, Bouzari H et al (2001) Repeat hepatectomy for colorectal liver metastases: a worthwhile operation? J Surg Oncol 76:127–132CrossRefPubMedGoogle Scholar
  8. 8.
    Petrowsky H, Gonen M, Jarnagin W et al (2002) Second liver resections are safe and effective treatment for recurrent hepatic metastases from colorectal cancer. A bi-institutional analysis. Ann Surg 235:863–871CrossRefPubMedGoogle Scholar
  9. 9.
    de Jong M, Mayo SC, Pulitano C et al (2009) Repeat curative intent liver surgery is safe and effective for recurrent colorectal liver metastasis: results from an international multi-institutional analysis. J Gastroint Surg 13:2141–2151CrossRefGoogle Scholar
  10. 10.
    Adam R, Pascal G, Azoulay D et al (2003) Liver resection for colorectal metastases. The third hepatectomy. Ann Surg 238:871–884CrossRefPubMedGoogle Scholar
  11. 11.
    Shaw MI, Rees M, Welsh FKS et al (2006) Repeat hepatic resection for recurrent colorectal liver metastases is associated with favourable long-term survival. Br J Surg 93:457–464CrossRefPubMedGoogle Scholar
  12. 12.
    Brachet D, Dermite E, Rouquette A et al (2009) Prognostic factors of survival in repeat liver resection for recurrent colorectal metastases: review of sixty-two cases treated at a single institution. Dis Colon Rectum 52:475–483PubMedGoogle Scholar
  13. 13.
    Adam R, Bismuth H, Castaing D et al (1997) Repeat hepatectomy for colorectal liver metastases. Ann Surg 225:51–62CrossRefPubMedGoogle Scholar
  14. 14.
    Imamura H, Kawasaki S, Miyagawa S et al (2000) Aggressive surgical approach to recurrent tumours after hepatectomy for metastatic spread of colorectal cancer to the liver. Surgery 127:528–535CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia 2011

Authors and Affiliations

  • Andrea Muratore
    • 1
  1. 1.Division of Hepato-Bilio-Pancreatic and Digestive SurgeryMauriziano “Umberto I” HospitalTurinItaly

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