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Carcinomi dei seni paranasali e delle fosse nasali

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Tumori della testa e del collo

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Riassunto

I tumori maligni nasosinusali, con o senza coinvolgimento del basicranio, sono affezioni poco comuni, stimate intorno all’0.8% di tutti i tumori maligni e intorno al 3% dei tumori maligni della testa e del collo [1]. Nonostante le diverse proposte di trattamento, rappresentate dalla chirurgia associata alla radioterapia e/o alla chemioterapia, la prognosi di queste neoplasie è critica. Ess a è condizionata dall’estensione della patologia alle strutture limitrofe come l’apice dell’orbita, l’encefalo, il seno cavernoso, oltre che da istologie particolarmente sfavorevoli come melanoma, carcinoma indifferenziato, carcinomi neuroendocrini, dove la chirurgia puó avere un ruolo prettamente palliativo o di recupero (salvataggio dopo fallimento terapeutico primario).

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Bibliografia

  1. Muir CS, Nectoux J (1980) Descriptive epidemiology of malignant neoplasm of nose, nasal cavities, middle ear and accessory sinuses. Clin Otolaryngol 5:195–277

    Article  PubMed  CAS  Google Scholar 

  2. Ketcham AS, Wilkins RH, Van Buren JM et al (1963) A combined intracranial facial approach to the paranasal sinuses. Am J Surg 166:698–703

    Article  Google Scholar 

  3. Lund VJ, Harrison DFN (1988) Craniofacial resection for tumors of the nasal cavity and paranasal sinuses. Am J Surg 156:187–190

    Article  PubMed  CAS  Google Scholar 

  4. Shah J, Kraus DH, Arbit E et al (1992) Craniofacial resection for tumors involving the anterior skull base. Otolaryngol Head Neck Surg 106:387–393

    Google Scholar 

  5. Howard DJ, Lund VJ, Wei WI (2006) Craniofacial resection for tumors of the nasal cavity and paranasal sinuses: a 25-year experience. Head & Neck 28:867–873

    Article  Google Scholar 

  6. Ganly I, Patel SG, Singh B et al (2005) Craniofacial resection for malignant paranasal sinus tumors: report of an international collaborative study. Head & Neck 27:575–584

    Article  Google Scholar 

  7. Ian G, Snehal GP, Bhuvanesh S (2005) Complications of craniofacial resection for malignant tumors of the skull base: report of an international collaborative study. Head & Neck 27:445–451

    Article  Google Scholar 

  8. Messerklinger W (1972) Technik und Moglichkeiten der Nasenendoskopie. HNO 20:133–135

    PubMed  CAS  Google Scholar 

  9. Castelnuovo P, Mauri S, Locatelli D et al (2001) Endoscopie repair of cerebrospinal fluid rhinorrhea: learning from our failures. Am J of Rhinol 15:333–342

    CAS  Google Scholar 

  10. Locatelli D, Rampa F, Acciardi I et al (2006) Endoscopic endonasal approaches for repair of cerebrospinal fluid leaks: nine-year experience. Neurosurgery 58:246–256

    Article  Google Scholar 

  11. Castelnuovo P, Pistochini A, Locatelli D (2006) Different surgical approaches to the sellar region: focusing on the “two nostrils four hands technique”. Rhinology 44:2–7

    PubMed  Google Scholar 

  12. Tomenzoli D, Castelnuovo P, Pagella P (2003) Different Endoscopic Surgical Strategies in the Management of Inerted Papilloma of the Sinonasal Tract: Experience with 47 Patients. Laryngoscope 113:1–8

    Article  Google Scholar 

  13. Stammberger H, Anderhuber W, Walch C et al (1999) Possibilties and limitations of endoscopic management of nasal and paranasal sinus malignancies. Acta Othorhinolaryngol Belg 53:199–205

    CAS  Google Scholar 

  14. Castelnuovo P, Battaglia P, Locatelli D et al i2006) Endonasal micro-endoscopic treatment of the malignant tumors of paranasal sinuses and anterior skull base. Operative Techniques in Otolaryngology 17:152–167

    Google Scholar 

  15. Nicolai P, Castelnuovo P, Lombardi D et al (2007) Role of endoscopic surgery in the management of selected malignant epithelial neoplasms of the naso-ethmoidal complex. Head Neck 29:1075–1082

    Article  PubMed  Google Scholar 

  16. Villaret AB, Yakirevitch A, Bizzoni A et al (2010) Endoscopic transnasal craniectomy in the management of selected sinonasal malignancies. Am J Rhinol Allergy 24:60–65

    Article  PubMed  Google Scholar 

  17. Castelnuovo P, Belli E, Bignami M et al (2006) Endoscopic nasal and anterior craniotomy resection for malignant nasoethmoid tumors involving the anterior skull base. Skull Base 117:15–18

    Article  Google Scholar 

  18. Nicolai P, Battaglia P, Bignami M et al (2008) Endoscopie surgery for malignant tumors of the sinonasal tract and adjacent skull-base: a 10-year experience. Am J Rhinol 22:308–316

    Article  PubMed  Google Scholar 

  19. Lund V, Howard DJ, Wei WI (2007) Endoscopic resection of malignant tumors of the nose and sinuses. Am J Rhinol 21:89–94

    Article  PubMed  Google Scholar 

  20. Million RR, Cassisi NJ (1992) Management of head and neck cancer. A multidisciplinary approach. JB Lippincot Co, Philadelphia

    Google Scholar 

  21. Wang CC (1983) Radiation therapy for head and neck neoplasms. Indications, techniques and results. J Wright, Boston

    Google Scholar 

  22. Gunderson LL, Tepper JE (2007) Clinical Radiation Oncology. Elsevier, Philadelphia

    Google Scholar 

  23. Halperin EC, Perez CA, Brady LW (2008) Principles and Practice of Radiation Oncology. LWW Philadelphia

    Google Scholar 

  24. Forastiere AA, Ang KK, Brizel D et al (2009) NCCN Clinical Practice Guidelines in Oncology. Head and neck cancer www.nccn.org <http://www.nccn.org>

  25. Frata P, Ponticelli P, Buffoli A et al (2008) Laradioterapia dei tumori della testa e del collo. Indicazioni e criteri guida AIRO www.radioterapiaitalia.it <http://www.radioterapiaitalia.it>

  26. Jesse RH (1965) Preoperative versus postoperative radiation in the treatment of squamous carcinomas of the paranasl sinuses. Am J Surg 110:552–556

    Article  PubMed  CAS  Google Scholar 

  27. Hu YH, Tu GY, Qi YQ et al (1982) Comparison of pre-and postoperative radiation in the combined treatment of carcinoma of maxillary sinus. Int J Radiat Oncol Biol Phys 8:1045–1049

    Article  PubMed  CAS  Google Scholar 

  28. Lindeman P, Eklund U, Petruson B (1987) Survival after surgical treatment in maxillary neoplasms of epithelial origin. J Laryngol Otol 101:564–568

    Article  PubMed  CAS  Google Scholar 

  29. Sisson GA Sr, Toriumi DM, Atiyah RA (1989) Paranasal sinus malignancy: a comprehensive update. Laryngoscope 99:143–150

    PubMed  Google Scholar 

  30. Waldron J, Witterick I (2003) Paranasal sinus cancer: caveats and controversies. World J Surg 27:849–855

    Article  PubMed  Google Scholar 

  31. Ang KK, Garden AS (2006) Radiotherapy for head and neck cancer. LWW, Philadelphia

    Google Scholar 

  32. Mazeron JJ, Chassagne D, Crook J et al (1988) Radiation therapy of carcinomas of the skin of nose and nasal vestibule: a report of 1676 cases by the Groupe Européen de Curietherapie Radiother Oncol 13:165

    Article  PubMed  CAS  Google Scholar 

  33. Langendijk JA, Poorter R, Leemans CR et al (2004) Radiotherapy of squamous cell carcinoma of the nasal vestibule. Int J Radiat Oncol Biol Phys 59:1319–1325

    Article  PubMed  Google Scholar 

  34. Kummer E, Rasch CR, Keus RB et al (2002) T stage as prognostic factor in inadiated localized squamous cell carcinoma of the nasal vestibule. Head Neck 24:268–273

    Article  PubMed  Google Scholar 

  35. Mendenhall WM, Stringer SP, Cassisi NJ et al (1999) Squamous cell carcinoma of the nasal vestibule. Head Neck 21:385–393

    Article  PubMed  CAS  Google Scholar 

  36. Chobe R, McNeese M, Weber R, Fletcher GH (1988) Radiation therapy for carcinoma of the nasal vestibule. Otolaryngol Head Neck Surg 98:67–71

    PubMed  CAS  Google Scholar 

  37. Wong CS, Cummings BJ, Elhakim T et al (1986) External irradiation for squamous cell carcinoma of the nasal vestibule. Int J RadiatiOncol Biol Phys 12:1943–1946

    Article  CAS  Google Scholar 

  38. Mak AC, Van Andel JG, Van Woerkom-Eijkenboom WM (1980) Radiation therapy of carcinoma of the nasal vestibule. Eur J Cancer 16:81–85

    Article  PubMed  CAS  Google Scholar 

  39. McCollough WM, Mendenhall NP, Parsons JT et al (1993) Radiotherapy alone for squamous cell carcinoma of the nasal vestibule: management of the primary site and regional lymphatics. Int J Radiat Oncol Biol Phys 26:73–79

    Article  PubMed  CAS  Google Scholar 

  40. Wang CC (1976) Treatment of carcinoma of the nasal vestibule by irradiation. Cancer 38:100–106

    Article  PubMed  CAS  Google Scholar 

  41. Rasch C, Keus R, Pameijer FA et al (1997) The potential impact of CT-MRI matching on tumor volume delineation in advanced head and neck cancer Int J Radiat Oncol Biol Phys 39:841–848

    Article  PubMed  CAS  Google Scholar 

  42. Nishioka T, Shiga T, Shirato H et al (2002) Image fusion between 18FDG-PET and MRI/CT for radiotherapy planning of oropharyngeal and nasopharyngeal carcinomas. Int J Radiat Oncol Biol Phys 53:1051–1057

    Article  PubMed  Google Scholar 

  43. Scarfone C, Lavely WC, Cmelak AJ et al (2004) Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging. J Nucl Med 45:543–552

    PubMed  Google Scholar 

  44. Katz TS, Mendenhall WM, Morris GC et al (2002) Malignant tumors of the nasal cavity and paranasal sinuses. Head Neck 24:821–829

    Article  PubMed  Google Scholar 

  45. Hawkins RB, Wynstra JH, Pilepich MV et al (1988) Carcinoma of the nasal cavity — results of primary and adjuvant radiotherapy. Int J Radiat Oncol Biol Phys 15:1129–1133

    Article  PubMed  CAS  Google Scholar 

  46. Jiang GL, Morrison VH, Garden AS et al (1998) Ethmoid sinus carcinomas: natural history and treatment results. Radiother Oncol 49:21–27

    Article  PubMed  CAS  Google Scholar 

  47. Waldron JN, Sullivan B, Warde P et al (1998) Etmoid sinus cancer: Twenty-nine cases managed with primary radiation therapy. Int J Radiat Oncol Biol Phys 41:361–369

    Article  PubMed  CAS  Google Scholar 

  48. Klintenberg C, Olofsson J, Helquist H et al (1984) Adenocarcinoma of the ethmoid sinuses. A review of 28 cases with special reference to wood dust exposure. Cancer 54:482–488

    CAS  Google Scholar 

  49. Heurtebise F, Bessede JP, Moreau JJ et al (1998) Adénocarcinome de l’ethmoide chez le travailleurs du bois. Etude retrospective de 25 cas. Revue société francaise d’ORL 51:21–26

    Google Scholar 

  50. Krengli M, Gabriele P, Turn L et al (1994) Laradioterapia esclusiva dei tumori dei seni paranasali. Analisi retrospettiva di 73 casi. La Radiologia Medica 88:291–294

    CAS  Google Scholar 

  51. George B, Salvan D, Luboinski Betal (1997) Tumeurs malignes de l’ethmoide. Série homogène de 41 cas opérés par voie mixte. Neurochirurgie 43:121–124

    CAS  Google Scholar 

  52. Roux FX, Pages JC, Nataf F et al (1997) Le tumeurs malignes ethmoido-sphenoidales. Cent trente cas. Etude rétrospective. Neurochirurgie 43:100–110

    CAS  Google Scholar 

  53. Moreau JJ, Bessede JP, Heurtebise F et al (1997) Adénocarcinome de l’ethmoide chez les travailleurs du bois. Etude rétrospective de 25 cas. Neurochirurgie 43:111–117

    CAS  Google Scholar 

  54. Harbo G, Grau C, Bundgaard T, et al (1997) Cancer of the nasal cavity and paranasal sinuses. A clinico-pathological study of 277 patients. Acta Oncol 36:45–50

    CAS  Google Scholar 

  55. Dulguerov P, Jacobsen MS, Allai AS (2001) Nasal and paranasal sinus carcinoma: are we making progress? Cancer 92:3012–3129

    Article  PubMed  CAS  Google Scholar 

  56. Knegt PP, Ah-See KW, vd Velden LA et al (2001) Adenocarcinoma of the ethmoidal sinus complex: surgical debulking and topical fluoro-uracil may be the optimal treatment Arch Otolaryngol Head Neck Surg 127:141–146

    PubMed  CAS  Google Scholar 

  57. Claus F, Boterberg T, Ost P et al (2002) Postoperative radiotherapy for adenocarcinoma of the ethmoid sinuses: treatment results for 47 patients. Int J Radiat Oncol Biol Phys 54:1089–1094

    Article  PubMed  Google Scholar 

  58. Jegoux F, Ferron CH, Malard O et al (2004) Adénocarcinome de l’ethmoide. Expérience nantaise. 80 cas. Place de la résection de la base du crane par voie trans-faciale. Ann Otolaryngol Chir Cervico-fac 121:213–221

    Google Scholar 

  59. Magrini SM, Nicolai P, Somensari A et al (2004) Which role for radiation therapy in ethmoid cancer? A retrospective analysis of 84 cases from a single institution. Tumori 90:573–578

    PubMed  Google Scholar 

  60. Choussy O, Ferron C, Védrine PO et al (2008) Adecarcinoma of ethmoid: a GETTEC retrospective multicenter study of 418 cases. The Laryngoscope 118:437–443

    Article  PubMed  Google Scholar 

  61. Mendenhall WM, Mendenhall CM, Riggs CEJ (2006) Sinonasal undifferentiated carcinoma. Am J Clin Oncol 29:27–31

    Article  PubMed  Google Scholar 

  62. Hoppe BS, Nelson CJ, Gomez DR et al (2008) Unresectable carcinoma of the paranasal sinuses: outcomes and toxicities. Int J Radiat Oncol Biol Phys 72:763–769

    Article  PubMed  Google Scholar 

  63. Olmi P, Cellai E, Chiavacci A et al (1986) Paranasal sinuses and nasal cavity cancer: different radiotherapeutic options, results and late damages. Tumori 72:589–595

    PubMed  CAS  Google Scholar 

  64. Logue JP, Slevin NJ (1991) Carcinoma of the nasal cavity and paranasal sinuses: an analysis of radical radiotherapy. Clin Oncol 3:84–89

    Article  CAS  Google Scholar 

  65. Mao ZD (1992) Long-term results of radiotherapy formalignat tumors of the nasal cavity — report of 317 patients. Zhonghua Zhong Liu Za Zhi 14:135–137

    PubMed  CAS  Google Scholar 

  66. Gabriele P, Orecchia R, Valente G et al (1994) Risultati della radioterapia nel trattamento dei tumori maligni della fossa nasale e del vestibolo. Radiol Med 87:853–857

    PubMed  CAS  Google Scholar 

  67. Hone SW, O’Leary TG, Maguire A et al (1995) Malignant sinonasal tumours. The Dublin Eye and Ear Hospital experience. Ir J Sc 164:139–141

    CAS  Google Scholar 

  68. Jansen EP, Keus RB, Hilgers FJM et al (2000) Does the combination of radiotherapy and debulking surgery favor survival in paranasal sinus carcinoma? Int J Radiat Oncol Biol Phys 48:27–35

    Article  PubMed  CAS  Google Scholar 

  69. Bhattacharyya N (2002) Cancer of the nasal cavity: survival and factors influencing prognosis. Arch Otolaryngol 128:1079–1083

    Google Scholar 

  70. Blanco AI, Clifford Chao KS, Ozygit G et al (2004) Carcinoma of paranasal sinuses: long-term outcomes with radiotherapy. Int J Radiat Oncol Biol Phys 59:51–58

    Article  PubMed  Google Scholar 

  71. Samant S, Robbins KT, Vang M et al (2004) Intrarterial cisplatin and concomitant radiation therapy followed by surgery for advanced paranasal sinus cancer. Arch Otolaryngol Head and Neck Surg 130:948–955

    Article  Google Scholar 

  72. Guntinas-Lichius O, Kreppel MP, Stuetzer H et al (2006) Single modality and multimodality treatment of nasal and paranasal sinuses cancer: a single institution experience of 229 patients. Eur J Surg Oncol 33:222–228

    PubMed  Google Scholar 

  73. Bristol I J, Ahamad A, Garden AS et al (2007) Postoperative radiotherapy for maxillary sinus cancer: long-term outcomes and toxicities of treatment. Int J Radiat Oncol Biol Phys 68:719–730

    Article  PubMed  Google Scholar 

  74. Chen AM, Daly ME, Bucci MK et al (2007) Carcinoma of the paranasal sinuses and nasal cavity treated with radiotherapy at a single institution over five decades: are we making improvement? Int J Radiat Oncol Biol Phys 69:141–147

    Article  PubMed  Google Scholar 

  75. Hoppe BS, Stegman LD, Zelefsky MJ et al (2007) Treatment of nasal cavity and paranasal sinus cancer with modern radiotherapy techniques in the postoperative setting-The MSKCC experience. Int J Radiat Oncol Biol Phys 67:691–702

    Article  PubMed  Google Scholar 

  76. Gabriele AM, Airoldi M, Garzaro M et al (2008) Stage III–IV sinonasal and nasal cavity carcinoma treated with threedimensional conformai radiotherapy. Tumori 94:320–326

    PubMed  Google Scholar 

  77. Khademi B, Moradi A, Hoseini S et al (2009) Malignant neoplasm of the sinonasal tract: report of 71 patients and literature review andanalysis. Oral Maxillofac Surg 13:191–199

    Article  PubMed  Google Scholar 

  78. Airoldi M, Garzaro M, Valente G et al (2009) Clinical and Biological prognostic factors in 179 caies with sinonasal carcinoma treated in the Italian Piedmont region. Oncology 4:262–269

    Article  Google Scholar 

  79. Madani I, Vakaet L, Boteberg T et al (2009) Intensitymodulated radiotherapy for sinonasal tumors: Ghent University Hospital update. Int J Radiat Oncol Biol Phys 73:424–432

    Article  PubMed  Google Scholar 

  80. Mendenhall WM (2009) Carcinoma of the nasal cavity and paranasal sinuses. The Laryngoscope 119:899–906

    Article  PubMed  Google Scholar 

  81. Dulguerov P, Allai AS (2006) Nasal and paranasal sinus carcinoma: how can we continue to make progress? Otolaryngol Head Neck Surg 14:67–72

    Google Scholar 

  82. Parsons JT, Bova FJ, Fitzgerald CR et al (1994) Severe dryeye syndrome following external beam irradiation. Int J Radiat Oncol Biol Phys 30:765–783

    PubMed  CAS  Google Scholar 

  83. Emami B, Lyman J, Brown A et al (1991) Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21:109–122

    PubMed  CAS  Google Scholar 

  84. Elkon D, Hightower SI, Lim Ml et al (1979) Esthesioneuroblastoma. Cancer 44:1087–1094

    Article  PubMed  CAS  Google Scholar 

  85. Kadish S, Goodman M, Wine CC (1976) Olfactory neuroblastoma: a clinical analysis of 17 cases. Cancer 37:1571–1576

    Article  PubMed  CAS  Google Scholar 

  86. Foote RL, Morita A, Ebersold MJ et al (1993) Esthesioneuroblastoma: the role of adjuvant radiation therapy. Int J Radiat Oncol Biol Phys 27:835–842

    Article  PubMed  CAS  Google Scholar 

  87. Rosenthal DI, Barker JLJ, El-Naggar AK et al (2004) Sinonasal malignancies with neuroendocrine differentiation. Cancer 101:2567–2573

    Article  PubMed  Google Scholar 

  88. Duthoy W, Boterberg T, Claus F et al (1979) Postoperative intensity-modulated radiotherapy in sinonasal carcinoma clinical results in 39 patients. Cancer 104:171

    Google Scholar 

  89. Grégoire V, De Neve W, Eisbruch A et al (2007) Intensity-Modulated Radiation Therapy for Head and Neck carcinoma. The Oncologist 12:555–564

    Article  PubMed  Google Scholar 

  90. Daly ME, Chen AM, Bucci MK et al (2007) Intensitymodulated radiation therapy for malignancies of the nasal cavity and paranasal sinuses. Int J Radiat Oncol Biol Phys 67:151–157

    Article  PubMed  Google Scholar 

  91. Hoppe BS, Wolden SL, Zelefsky MJ et al (2008) Postoperative intensity-modulated radiation therapy for cancers of the paranasal sinuses, nasal cavity, and lacrimal glands: technique, early outcomes, and toxicity. Head and Neck 30:925–932

    Article  PubMed  Google Scholar 

  92. Mock U, George D, Bogner J et al (2004) Treatment planning comparison of conventional, 3D conformai and intensity-modulated photon (IMRT) and proton therapy for paranasal sinus carcinoma. Int J Radiat Oncol Biol Phys 58:147–154

    Article  PubMed  Google Scholar 

  93. Tsien C, Eisbruch A, Mcshan D et al (2003) IMRT for locally advanced paranasal sinus tumors: incorporating clinical decisions in the optimizations process. Int J Radiat Oncol Biol Phys 55:776–784

    Article  PubMed  Google Scholar 

  94. Barnes L, Evenson J, Reichart P et al (2005) World Health Organization classification of tumors: pathology and genetics-head and neck tumors. IARC Press, Lyon

    Google Scholar 

  95. Mhawech P, Berczy M, Assaly M et al (2004) Human achaete-scute homologue (hASHl) mRNA level as a diagnostic marker to distinguish esthesioneuroblastoma from poorly differentiated tumors arising in the sinonasal tract. Am J Clin Pathol 122:100–105

    Article  PubMed  Google Scholar 

  96. Miyamoto RC, Gleich LL, Biddinger PW et al (2000) Esthesioneuroblastoma and sinonasal undifferentiated carcinoma: impact of histological grading and clinical staging on survival and prognosis. Laryngoscope 110:1262–1265

    Article  PubMed  CAS  Google Scholar 

  97. McHroy EA Jr, Buckner JC, Lewis JE (1998) Chemotherapy for advanced esthesioneuroblastoma: the Mayo Clinic experience. Neurosurgery 42:1023–1027

    Article  Google Scholar 

  98. Porter AB, Bernold DM, Giannini C et al (2008) Retrospective review of adjuvant chemotherapy for esthesioneuroblastoma. J Neurooncol 90:201–204

    Article  PubMed  Google Scholar 

  99. Musy PY, Reibel JF, Levine PA (2002) Sinonasal undifferentiated carcinoma: the search for a better outcome. Laryngoscope 112:1450–1455

    Article  PubMed  Google Scholar 

  100. Rischin D, Porceddu S, Peteri L et al (2004) Promising results with chemoradiation in patients with sinonasal un differentiated carcinorna Head Neck 26:435–441

    Article  PubMed  Google Scholar 

  101. Laurie SA, Licitra L (2006) Systemic therapy in the palliative management of advanced salivary gland cancers. J Clin Oncol 24:2673–2678

    Article  PubMed  CAS  Google Scholar 

  102. McKay SP, Shibuya TY, Armstrong WB et al (2007) Cell carcinoma of the paranasal sinuses and skull base. Am J Otolaryngol 28:294–301

    Article  PubMed  Google Scholar 

  103. Licitra L, Suardi S, Bossi P et al (2004) Prediction of TP53 status for primary cisplatin, fluorouracil, and leucovorin chemotherapy in ethmoid sinus intestinal-type adenocarcinoma. J Clin Oncol 22:4901–4906

    Article  PubMed  CAS  Google Scholar 

  104. Björk-Eriksson T, Mercke C, Petruson B et al (1992) Potential impact on tumor control and organ preservation with cisplatin and 5-fluorouracil for patients with advanced tumors of the paranasal sinuses and nasal fossa. A prospective pilot study. Cancer 70:2615–2620

    Google Scholar 

  105. Licitra L, Locati LD, Cavina R et al (2003) Primary chemotherapy followed by anterior craniofacial resection and radiotherapy for paranasal cancer. Ann Oncol 14:367–372

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Clinica Otorinolaringoiatrica, Ospedale di Circolo e Fondazione Macchi, Università degli Studi dell’Insubria, Varese, Itaiia

    Paolo Castelnuovo

  2. Direzione Operativa di Radioterapia, Istituto per la Ricerca e Cura del Cancro, Candiolo (TO), Italia

    Pietro Gabriele

  3. Dipartimento di medicina oncologica, S.S. Trattamento Medico dei Tumori Testa e Collo, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italia

    Paolo Bossi

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Castelnuovo, P. et al. (2011). Carcinomi dei seni paranasali e delle fosse nasali. In: Tumori della testa e del collo. Springer, Milano. https://doi.org/10.1007/978-88-470-1806-8_27

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