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The Higher Prevalence of B-Cell Non-Hodgkin’s Lymphoma in HCV-Positive Patients with and Without Cryoglobulinemia

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HCV Infection and Cryoglobulinemia

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Abstract

Hepatitis C virus (HCV) is a major cause of liver-related morbidity and is increasingly linked to a subgroup of B cell lymphoproliferative disorders. On the strength of epidemiological data, emerging biological investigation, and clinical observations, HCV appears to be involved in the pathogenesis of B-cell non-Hodgkin’s lymphoma (NHL) in a subset of patients. Morphologically, HCV-associated NHLs encompass a variety of histological subtypes, including marginal zone, small lymphocytic lymphoma/chronic lymphocytic leukemia, lymphoplasmacytic lymphoma, and diffuse large B-cell lymphoma. Remarkably, some HCV-associated NHLs are highly responsive to antiviral therapy.

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Authors and Affiliations

  1. Department of Internal Medicine and Clinical Oncology, University of Bari Medical School, Bari, Italy

    Franco Dammacco

  2. Liver Unit, Department of Biomedical Sciences and Clinical Oncology, University of Bari Medical School, Bari, Italy

    Domenico Sansonno

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  1. Franco Dammacco
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  2. Domenico Sansonno
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Correspondence to Franco Dammacco .

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Editors and Affiliations

  1. , Department of Internal Medicine and Clin, University of Bari, Piazza Giulio Cesare 11, Bari, 70124, Italy

    Franco Dammacco

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Dammacco, F., Sansonno, D. (2012). The Higher Prevalence of B-Cell Non-Hodgkin’s Lymphoma in HCV-Positive Patients with and Without Cryoglobulinemia. In: Dammacco, F. (eds) HCV Infection and Cryoglobulinemia. Springer, Milano. https://doi.org/10.1007/978-88-470-1705-4_34

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  • DOI: https://doi.org/10.1007/978-88-470-1705-4_34

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  • Publisher Name: Springer, Milano

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  • Online ISBN: 978-88-470-1705-4

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