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Radiofarmaci per tomografia a emissione di positroni

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Book cover Fondamenti di medicina nucleare

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Oltre a radionuclidi gamma-emittenti, sono utilizzati per uso diagnostico anche composti che decadono mediante emissione di positroni (β+) dal nucleo. La peculiarità cui è legato l’impiego in medicina nucleare di questi nuclei radioattivi è costituita dalla radiazione che origina dall’evento di annichilazione fra particella β+ e particella β, che avviene dopo un certo percorso nella materia (denominato positron range), rispetto al punto esatto di emissione del β+ stesso. Questa radiazione comporta l’emissione contemporanea di due raggi γ ad alta energia (511 keV) che si dipartono dal punto di annichilazione con un angolo di circa 180°, caratteristica che costituisce la base del principio fisico della rivelazione adottata in tomografia mediante emissione di positroni (PET) (vedi Capitolo 12).

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Lorenzoni, A., Orsini, F., Salvadori, P.A. (2010). Radiofarmaci per tomografia a emissione di positroni. In: Volterrani, D., Mariani, G., Erba, P.A. (eds) Fondamenti di medicina nucleare. Springer, Milano. https://doi.org/10.1007/978-88-470-1685-9_5

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  • DOI: https://doi.org/10.1007/978-88-470-1685-9_5

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-1684-2

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