Abstract
Conventional nuclear medicine investigations of the gastrointestinal (GI) tract are not commonly performed in routine clinical practice, although prevalence of disorders affecting the upper gastrointestinal tract is quite high ranging from 15% to 40% in European countries. Most diagnostic tests used to differentiate organic from nonorganic cause are invasive (endoscopy, manometry, pH monitoring) and may be not well tolerated by some patients. Radionuclide procedures are non-invasive and allow characterizing functional and motility abnormalities of the esophagus and stomach. They are easy to perform, widely available and deliver low radiation burden to the patient at low cost. Despite the lack of standardization, both esophageal transit studies and gastric emptying scintigraphy have shown excellent diagnostic results and are helpful complementary tools for the clinician at diagnosis and/or follow-up after surgery or conservative management.
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References
Ziessman HA, O’Malley JP, Thrall JH (2006) Nuclear medicine: The requisite. Radiology, 3rd edn. Elsevier Mosby, Philadelphia, PA, USA
Mariani G, Boni G, Barreca M et al (2004) Radionuclide gastrooesophageal motor studies. J Nucl Med 45:1004–1028
Nakajima K, Inali A, Hiramatsu T et al (2009) Esophageal transit scintigraphy and structured questionnaire in patients with systemic sclerosis with endoscopically proven reflux esophagitis. Ann Nucl Med October 24 Epub ahead of print
Boz AB, Aydin F, Celmeli F et al (2009) Does gastroesophageal reflux scintigraphy correlate with clinical findings in children with chronic cough? Nulc Med Commun 30: 802–806
Morigeri C, Bhattacharya A, Mukhopadhyay K et al (2008) Radionuclide scintigraphy in the evaluation of gastrooesophageal reflux in symptomatic and asymptomatic pre-term infants. Eur J Nucl Med Mol Imaging 35:1659–1665
International Pediatric Endosurgery Group (IPEG) Standard and Safety Committee (2009) IPEG guidelines for the surgical treatment of pediatric gastrooesophageal reflux disease (GERD). J Laparoendosc Adv Surg Tech A 19:x–xiii
Ravelli AM, Panarotto MB, Verdoni L et al (2006) Pulmonary aspiration shown by scintigraphy in gastrooesophageal refluxrelated respiratory disease. Chest 130:1520–1526
Abell TL, Camilleri M, Donohoe K et al (2008) Consensus recommendations for gastric emptying scintigraphy: a joint report of the American Neurogastroenterology and Motility Society and the Society of Nuclear Medicine. Am J Gastroenterol 103:753–763
Waseem S, Moshiree B, Draganov PV (2009) Gastroparesis: current diagnostic challenges and management considerations. World J Gastroenterol 15:25–37
Szarka LA, Camilleri M (2009) Methods for measurement of gastric motility. Am J Physiol Gastrointest Liver Physiol 296:461–475
Donohoe KJ, Maurer AH, Ziessman HA et al (2009) Procedure guideline for adult solid-meal gastric-emptying study 3.0. J Nucl Med Technol 3:196–200
Mariani G, Pauwels EKJ, AlSharif A et al (2008) Radionuclide evaluation of the lower gastrointestinal tract. J Nucl Med 49:776–787
Howarth DM (2006) The role of nuclear medicine in the detection of acute gastrointestinal bleeding. Semin Nucl Med 36:133–146
Ford PV, Bartold SP, Fink-Bennett DM et al (1999) Society of Nuclear Medicine procedure guideline for gastrointestinal bleeding and Meckel’s diverticulum scintigraphy 1.0. J Nucl Med 40:1226–1232
Kiratli PO, Aksoy T, Bozkurt MF et al (2009) Detection of ectopic gastric mucosa using 99mTc pertechnetate: review of the litterature. Ann Nucl Med 23:97–105
Rerksuppaphol S, Hutson JM, Oliver MR (2004) Ranitidineenhanced 99m technetium pertechnetate imaging in children improves the sensitivity of identifying heterotopic gastric mucosa in Meckel’s diverticulum. Pediatr Surg Int 20:323–325
Balon HR, Brill DR, Fink-Bennett DM et al (2001) Society of Nuclear Medicine procedure guideline for hepatobiliary scintigraphy 3.0. J Nucl Med 38:1654–1657
Nadel HR (1996) Hepatobiliary scintigraphy in children. Semin Nucl Med 26:25–42
Yang JG, Ma DQ, Peng Y et al (2009) Comparison of different diagnostic methods for differentiating biliary atresia from idiopathic neonatal hepatitis. Clin Imaging 33:439–446
Riccabona M, Avni FE, Blickman JG et al (2009) Imaging recommendations in paediatric uroradiology. Pediatr Radiol 39:891–898
Koff SA (2008) Requirements for accurately diagnosing chronic partial upper urinary tract obstruction in children with hydronephrosis. Pediatr Radiol 38(suppl 1):S41–S48
Gordon I, Colarinha P, Fettich J et al (2001) Guidelines for standard and diuretic renogram in children. Eur J Nucl Med 28:BP21–BP30
Piepsz A, Colarinha P, Gordon I et al (2001) Guidelines for glomerular filtration rate determination in children. Eur J Nucl Med 28:BP31–BP36
Boubaker A, Prior JO, Meuwly JY et al (2006) Radionuclide investigations of the urinary tract in the era of multimodality imaging. J Nucl Med 47:1819–1836
Piepsz A, Colarinha P, Gordon I et al (2001) Guidelines on 99m Tc-DMSA scintigraphy in children. Eur J Nucl Med 28:BP37–41
Fettich J, Colarinha P, Fischer S et al (2003) Guidelines for direct radionuclide cystography in children. Eur J Nucl Med Mol Imaging 30:B39–44
Gordon I, Colarinha P, Fettich J et al (2001) Guidelines for indirect radionuclide cystography. Eur J Nucl Med 28:BP16–20
Taylor AT, Blaufox MD, Dubovsky EV et al (1998) Society of Nuclear Medicine procedure guideline for diagnosis of renovascular hypertension 3.0. J Nucl Med 39:1297–1302
A report of the Amsterdam Forum on the Care of the Live Kidney Donor (2005) Data and Medical Guidelines. Transplantation 79:S53–S66
Prigent A (2008) Monitoring renal function and limitations of renal function tests. Semin Nucl Med 38:32–46
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Boubaker, A. (2010). Conventional Nuclear Medicine in the Evaluation of Gastrointestinal and Genitourinary Tract Disorders. In: Hodler, J., Zollikofer, C.L., Von Schulthess, G.K. (eds) Diseases of the Abdomen and Pelvis 2010–2013. Springer, Milano. https://doi.org/10.1007/978-88-470-1637-8_28
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DOI: https://doi.org/10.1007/978-88-470-1637-8_28
Publisher Name: Springer, Milano
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