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Infections of Peritoneum, Mediastinum, Pleura, Wounds, and Urinary Tract

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Infection Control in the Intensive Care Unit
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Abstract

Intra-abdominal infections (IAIs) are defined as an inflammatory response of the peritoneum to microorganisms and their toxins, which results in purulent exudate in the abdominal cavity. They have two major manifestations: generalized peritonitis and IA abscess. Mortality rates for peritonitis, regardless of diagnostic and therapeutic developments in recent years, remain unacceptably high and still represent one of the greatest challenges for surgeons. Drainage, debridement, and definitive surgical management are the usual consecutive steps to be carried out, but in many circumstances, the procedure has to be tailored to the individual patient. Successful source control and antibiotic management is associated with illness resolution. Progression or failure to resolve organ dysfunction suggests disease persistence and the need for further intervention. Particular interest has been given to severe acute pancreas and its diagnosis and management, as well as to mediastinitis and pleural infection disease. Furthermore, we discuss the two most important sources of infection in surgery: wound and urinary tract.

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References

  1. Bosscha K, van Vroonhoven JMV, van der Werken C (1999) Surgical management of severe secondary peritonitis. Br J Surg 86:1371–1377

    Article  PubMed  CAS  Google Scholar 

  2. Sganga G, Brisinda G, Castagneto M (2001) Peritonitis: priorities and management strategies. In: van Saene HKF, Sganga G, Silvestri L (eds) Infection in the critically ill: an ongoing challenge. Springer, Berlin, pp 23–33

    Google Scholar 

  3. Sganga G (2000) Sepsi addominali chirurgiche e insufficienza multiorgano (MOFS). Edizioni Systems Comunicazioni, Milan

    Google Scholar 

  4. Bone RG, Balk RA, Cerra FB et al (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101:1644–1655

    Article  PubMed  CAS  Google Scholar 

  5. Pieracci FM, Barie PS (2007) Intra-abdominal infections. Curr Opin Crit Care 13:440–449

    Article  PubMed  Google Scholar 

  6. Solomkin JS, Mazuski JE, Baron EJ et al (2003) Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections. Clin Infect Dis 37:997–1005

    Article  PubMed  Google Scholar 

  7. Brook I (2008) Microbiology and Management of Abdominal Infections. Dig Dis Sci 53:2585–2591

    Article  PubMed  Google Scholar 

  8. Krepel CJ, Gohr CM, Edmiston CE, Condon RE (1995) Surgical sepsis: constancy of antibiotic susceptibility of causative organisms. Surgery 117:505–509

    Article  PubMed  CAS  Google Scholar 

  9. Sganga G, Brisinda G, Castagneto M (2000) Nosocomial fungal infections in surgical patients: risk factors and treatment. Minerva Anestesiol 66(Suppl 1):71–77

    Google Scholar 

  10. Wheeler AP, Bernard GR (1999) Treating patients with severe sepsis. N Engl J Med 340:207–214

    Article  PubMed  CAS  Google Scholar 

  11. Mannick JA, Rodrick ML, Lederer JA (2001) The immunologic response to injury. J Am Coll Surg 193:237–244

    Article  PubMed  CAS  Google Scholar 

  12. Knoferl MW, Angele MK, Diodato MD et al (2002) Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis. Ann Surg 235:105–112

    Article  PubMed  Google Scholar 

  13. Sganga G, van Saene HKF, Brisinda G, Castagneto M (2001) Bacterial translocation. In: van Saene HKF, Sganga G, Silvestri L (eds) Infection in the critically ill: an ongoing challenge. Springer, Berlin, pp 35–45

    Google Scholar 

  14. Gregor P, Prodger JD (1988) Mead Johnson Critical Care Symposium for the Practic Surgeon. 4. Abdominal crisis in the intensive care unit. Can J Surg 31:331–332

    PubMed  CAS  Google Scholar 

  15. Gajic O, Errutia LE, Sewan H et al (2002) Acute abdomen in the medical intensive care unit. Crit Care Med 30:1187–1190

    Article  PubMed  Google Scholar 

  16. Kollef MH, Allen BT (1994) Determinants of outcome for patients in the medical intensive care unit requiring abdominal surgery: a prospective, single-center study. Chest 106:1822–1828

    Article  PubMed  CAS  Google Scholar 

  17. Velmahos GC, Kamel E, Berne TV et al (1999) Abdominal computed tomography for the diagnosis of intra-abdominal sepsis in critically injured patients: fishing in murky waters. Arch Surg 134:831–836

    Article  PubMed  CAS  Google Scholar 

  18. Mokart D, Merlin M, Sannini A et al (2005) Procalcitonin, interleukin 6 and systemic inflammatory response syndrome (SIRS): early markers of postoperative sepsis after major surgery. Br J Anaesthesiol 94:767–773

    Article  CAS  Google Scholar 

  19. Wickel DJ, Cheadle WG, Mercer-Jones MA, Garrison RN (1997) Poor outcome from peritonitis is caused by disease acuity and organ failure, not recurrent peritoneal infection. Ann Surg 225:744–756

    Article  PubMed  CAS  Google Scholar 

  20. Anbidge AE, Lynch D, Wison SR (2003) US of the peritoneum. Radiographics 23:663–684

    Article  Google Scholar 

  21. Go HL, Baarslag HJ, Vermeulen H et al (2005) A comparative study to validate the use of ultrasonography and computed tomography in patients with post-operative intra-abdominal sepsis. Eur J Radiol 54:383–387

    Article  PubMed  CAS  Google Scholar 

  22. Whitehouse JS, Weigelt JA (2009) Diagnostic peritoneal lavage: a review of indications, technique, and interpretation. Scandinavian J Trauma Resuscitation Emerg Med 17:13

    Article  Google Scholar 

  23. Lin WY, Chao TH, Wang SJ (2002) Clinical features and gallium scan in the detection of post-surgical infection in the elderly. Eur J Nucl Med 29:371–375

    Article  CAS  Google Scholar 

  24. Shih-Chuan T, Te-Hsin C, Lin WY, Shyh-Jen W (2001) Abdominal abscesses in patients having surgery an application of Ga-67 scintigraphic and computed tomographic scanning. Clin Nucl Med 26:761–776

    Article  Google Scholar 

  25. Marshall J, Maier RV, Jimenez M, Dellinger EP (2004) Source control in the management of severe sepsis and septic shock: an evidence-based review. Crit Care Med 32(Suppl 11):S513–S526

    Article  PubMed  Google Scholar 

  26. Soares-Weiser K, Paul M, Brezis M, Leibovici L (2002) Antibiotic treatment for spontaneous bacterial peritonitis. BMJ 324:100–102

    Article  PubMed  CAS  Google Scholar 

  27. Solomkin JS, Wilson SE, Christou N et al (2001) Results of a clinical trial of clinafloxacin versus imipenem/cilastatin for intraabdominal infections. Ann Surg 233:79–87

    Article  PubMed  CAS  Google Scholar 

  28. Mazuski JE (2007) Antimicrobial treatment for intra-abdominal infections. Expert Opin Pharmacother 8(17):2933–2945

    Article  PubMed  CAS  Google Scholar 

  29. Laterre PF (2008) Progress in medical management of intra-abdominal infection. Curr Opin Infect Dis 21(4):393–398

    Article  PubMed  Google Scholar 

  30. Cohen J (2000) Combination antibiotic therapy for severe peritonitis. Lancet 356:1539–1540

    Article  PubMed  CAS  Google Scholar 

  31. Holzheimer RG, Dralle H (2001) Paradigm change in 30 years peritonitis treatment. A review on source control. Eur J Med Res 6:161–168

    PubMed  CAS  Google Scholar 

  32. Schein M, Marshall J (2004) Source control for surgical infections. World J Surg 28(7):638–645

    Article  PubMed  Google Scholar 

  33. Rivers E, Nguyen B, Havstad S et al (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368–1377

    Article  PubMed  CAS  Google Scholar 

  34. Platell C, Papadimitriou JM, Hall JC (2000) The influence of lavage on peritonitis. J Am Coll Surg 191:672–680

    Article  PubMed  CAS  Google Scholar 

  35. Sganga G, Brisinda G, Castagneto M (2002) Trauma operative procedures: timing of surgery and priorities. In: Gullo A (ed) Critical care medicine. Springer, Berlin, pp 447–467

    Google Scholar 

  36. Levison MA, Zeigler D (1991) Correlation of APACHE II score, drainage technique and outcome in postoperative intra-abdominal abscess. Surg Gynecol Obstet 172:89–94

    PubMed  CAS  Google Scholar 

  37. Baril NB, Ralls PW, Wren SM et al (2000) Does an infected peripancreatic fluid collection or abscess mandate operation? Ann Surg 231:361–367

    Article  PubMed  CAS  Google Scholar 

  38. Brisinda G, Maria G, Ferrante A, Civello IM (1999) Evaluation of prognostic factors in patients with acute pancreatitis. Hepatogastroenterology 46:1990–1997

    PubMed  CAS  Google Scholar 

  39. Baron TH, Morgan DE (1999) Acute necrotizing pancreatitis. N Engl J Med 340:1412–1417

    Article  PubMed  CAS  Google Scholar 

  40. Beger HG, Rau B, Mayer J, Pralle U (1997) Natural course of acute pancreatitis. World J Surg 21:130–135

    Article  PubMed  CAS  Google Scholar 

  41. Bradley EL III (1993) A clinically based classification system for acute pancreatitis. Summary of the international symposium on acute pancreatitis, Atlanta, GA, Sept. 11–13, 1992. Arch Surg 128:586–590

    Google Scholar 

  42. Marotta F, Geng TC, Wu CC, Barbi G (1996) Bacterial translocation in the course of acute pancreatitis: beneficial role of nonabsorbable antibiotics and Lactinol enemas. Digestion 57:446–452

    Article  PubMed  CAS  Google Scholar 

  43. Foitzik T, Fernandez-del Castillo C, Ferraro MJ et al (1995) Pathogenesis and prevention of early pancreatic infection in experimental acute necrotizing pancreatitis. Ann Surg 222:179–185

    Article  PubMed  CAS  Google Scholar 

  44. Isenmann R, Schwarz M, Rau B et al (2002) Characteristics of infection with Candida species in patients with necrotizing pancreatitis. World J Surg 26(3):372–376

    Article  PubMed  Google Scholar 

  45. Bradley EL III (1994) Surgical indications and techniques in necrotizing pancreatitis. In: Bradley EL III (ed) Acute pancreatitis: diagnosis and therapy. Raven Press, New York, pp 105–117

    Google Scholar 

  46. Paye F, Rotman N, Radier C et al (1998) Percutaneous aspiration for bacteriological studies in patients with necrotizing pancreatitis. Br J Surg 85:755–759

    Article  PubMed  CAS  Google Scholar 

  47. Rau B, Pralle U, Mayer JM, Beger HG (1998) Role of ultrasonographically guided fine-needle aspiration cytology in diagnosis of infected pancreatic necrosis. Br J Surg 85:179–184

    Article  PubMed  CAS  Google Scholar 

  48. Mithofer K, Fernandez-del Castillo C, Ferraro MJ et al (1996) Antibiotic treatment improves survival in experimental acute necrotizing pancreatitis. Gastroenterology 110:232–240

    Article  PubMed  CAS  Google Scholar 

  49. Sainio V, Kemppainen E, Puolakkainen P et al (1995) Early antibiotic treatment in acute necrotising pancreatitis. Lancet 346:663–667

    Article  PubMed  CAS  Google Scholar 

  50. Luiten EJ, Hop WC, Lange JF, Bruining HA (1995) Controlled clinical trial of selective decontamination for the treatment of severe acute pancreatitis. Ann Surg 222:57–65

    Article  PubMed  CAS  Google Scholar 

  51. Luiten EJ, Hop WC, Lange JF, Bruining HA (1997) Differential prognosis of gram-negative versus gram-positive infected and sterile pancreatic necrosis: results of a randomized trial in patients with severe acute pancreatitis treated with adjuvant selective decontamination. Clin Infect Dis 25:811–816

    Article  PubMed  CAS  Google Scholar 

  52. Pederzoli P, Bassi C, Vesentini S, Campedelli A (1993) A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem. Surg Gynecol Obstet 176:480–483

    PubMed  CAS  Google Scholar 

  53. Ho HS, Frey CF (1997) The role of antibiotic prophylaxis in severe acute pancreatitis. Arch Surg 132:487–493

    Article  PubMed  CAS  Google Scholar 

  54. Bassi C, Falconi M, Talamini G et al (1998) Controlled clinical trial of pefloxacin versus imipenem in severe acute pancreatitis. Gastroenterology 115:1513–1517

    Article  PubMed  CAS  Google Scholar 

  55. McClave SA, Snider H, Owens N, Sexton LK (1997) Clinical nutrition in pancreatitis. Dig Dis Sci 42:2035–2044

    Article  PubMed  CAS  Google Scholar 

  56. Kalfarentzos F, Kehagias J, Mead N et al (1997) Enteral nutrition is superior to parenteral nutrition in severe acute pancreatitis: results of a randomized prospective trial. Br J Surg 84:1665–1669

    Article  PubMed  CAS  Google Scholar 

  57. Windsor AC, Kanwar S, Li AG et al (1998) Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis. Gut 42:431–435

    Article  PubMed  CAS  Google Scholar 

  58. Bozzetti F, Braga M, Gianotti L et al (2001) Postoperative enteral versus parenteral nutrition in malnourished patients with gastrointestinal cancer: a randomised multicentre trial. Lancet 358:1487–1492

    Article  PubMed  CAS  Google Scholar 

  59. Warshaw AL (2000) Pancreatic necrosis. To debride or not to debride–that is the question. Ann Surg 232:627–629

    Article  PubMed  CAS  Google Scholar 

  60. Buchler MW, Gloor B, Muller CA et al (2000) Acute necrotizing pancreatitis: treatment strategy according to the status of infection. Ann Surg 232:619–626

    Article  PubMed  CAS  Google Scholar 

  61. Farkas G, Marton J, Mandi Y, Szederkenyi E (1996) Surgical strategy and management of infected pancreatic necrosis. Br J Surg 83:930–933

    Article  PubMed  CAS  Google Scholar 

  62. Ashley SW, Perez A, Pierce EA et al (2001) Necrotizing pancreatitis. Contemporary analysis of 99 consecutive cases. Ann Surg 234:572–580

    Article  PubMed  CAS  Google Scholar 

  63. Gloor B, Muller CA, Worni M et al (2001) Pancreatic infection in severe pancreatitis. The role of fungus and multiresistant organisms. Arch Surg 136:592–596

    Article  PubMed  CAS  Google Scholar 

  64. Doglietto GB, Gui D, Pacelli F et al (1994) Open vs closed treatment of secondary pancreatic infection. A review of 42 cases. Arch Surg 129:689–693

    Article  PubMed  CAS  Google Scholar 

  65. Kriwanek S, Gschwantler M, Beckerhinn P et al (1999) Complications after surgery for necrotising pancreatitis: risk factors and prognosis. Eur J Surg 165:952–957

    Article  PubMed  CAS  Google Scholar 

  66. Dervenis C, Bassi C (2000) Evidence-based assessment of severity and management of acute pancreatitis. Br J Surg 87:257–258

    Article  PubMed  CAS  Google Scholar 

  67. Tsiotos GG, Luque-de Leon E, Sarr MG (1998) Long-term outcome of necrotizing pancreatitis treated by necrosectomy. Br J Surg 85:1650–1653

    Article  PubMed  CAS  Google Scholar 

  68. del Castillo CF, Rattner DW, Makary MA et al (1998) Debridement and closed packing for treatment of necrotizing pancreatitis. Ann Surg 228:676–684

    Article  Google Scholar 

  69. Farkas G (2000) Pancreatic head mass: how can we treat it? Acute pancreatitis: surgical treatment. JOP J Pancreas 1(Suppl 3):138–142

    CAS  Google Scholar 

  70. Mithofer K, Mueller PR, Warshaw AL (1997) Interventional and surgical treatment of pancreatic abscess. World J Surg 21:162–168

    Article  PubMed  CAS  Google Scholar 

  71. Widdison AL, Karanjia ND (1993) Pancreatic infection complicating acute pancreatitis. Br J Surg 80:148–154

    Article  PubMed  CAS  Google Scholar 

  72. Lumsden A, Bradley EL III (1990) Secondary pancreatic infections. Surg Gynecol Obstet 170:459–467

    PubMed  CAS  Google Scholar 

  73. Aranha GV, Prinz RA, Greenlee HB (1982) Pancreatic abscess: an unresolved surgical problem. Am J Surg 144:534–538

    Article  PubMed  CAS  Google Scholar 

  74. Warshaw AL, Jin G (1985) Improved survival in 45 patients with pancreatic abscess. Ann Surg 202:408–417

    Article  PubMed  CAS  Google Scholar 

  75. Brisinda G, Mazzari A, Crocco A et al (2011) Open pancreatic necrosectomy in the multidisciplinary management of postinflammatory necrosis. Ann Surg 253(5):1049–1051

    Article  PubMed  Google Scholar 

  76. Ross Carter C, McKay CJ, Imrie CW (2000) Percutaneous necrosectomy and sinus tract endoscopy in the management of infected pancreatic necrosis: an initial experience. Ann Surg 232:175–180

    Article  Google Scholar 

  77. Kjossev KT, Losanoff JE (2001) Laparoscopic treatment of severe acute pancreatitis. Surg Endosc 15:1239–1240

    PubMed  CAS  Google Scholar 

  78. Freeny PC, Hauptmann E, Althaus SJ et al (1998) Percutaneous CT-guided catheter drainage of infected acute necrotizing pancreatitis: techniques and results. AJR Am J Roentgenol 170:969–975

    PubMed  CAS  Google Scholar 

  79. Baron TH, Morgan DE (1997) Organized pancreatic necrosis: definition, diagnosis, and management. Gastroenterol Int 10:167–178

    Google Scholar 

  80. Wada K, Takada T, Hirata K et al (2010) Treatment strategy for acute pancreatitis. J Hepatobiliary Pancreat Sci 17:79–86

    Article  PubMed  Google Scholar 

  81. Zhu JF, Fan XH, Zhang XH (2001) Laparoscopic treatment of severe acute pancreatitis. Surg Endosc 15:146–148

    Article  PubMed  CAS  Google Scholar 

  82. Clancy CJ, Nguyen MH, Morris AJ (1997) Candidal mediastinitis: an emerging clinical entity. Clin Infect Dis 25:608–613

    Article  PubMed  CAS  Google Scholar 

  83. Gamlin F, Caldicott LD, Shah MV (1994) Mediastinitis and sepsis syndrome following intubation. Anaesthesia 49:883–885

    Article  PubMed  CAS  Google Scholar 

  84. Isaacs L, Kotton B, Peralta MM Jr et al (1993) Fatal mediastinal abscess from upper respiratory infection. Ear Nose Throat J 72:620–622

    PubMed  CAS  Google Scholar 

  85. Becker M, Zbaren P, Hermans R et al (1997) Necrotizing fasciitis of the head and neck: role of CT in diagnosis and management. Radiology 202:471–476

    PubMed  CAS  Google Scholar 

  86. Brunelli A, Sabbatini A, Catalini G, Fianchini A (1996) Descending necrotizing mediastinitis. Surgical drainage and tracheostomy. Arch Otolaryngol Head Neck Surg 122:1326–1329

    Article  PubMed  CAS  Google Scholar 

  87. Corsten MJ, Shamji FM, Odell PF et al (1997) Optimal treatment of descending necrotising mediastinitis. Thorax 52:702–708

    Article  PubMed  CAS  Google Scholar 

  88. Baldwin RT, Radovancevic B, Sweeney MS (1992) Bacterial mediastinitis after heart transplantation. J Heart Lung Transpl 11:545–549

    CAS  Google Scholar 

  89. El Oakley RM, Wright JE (1996) Postoperative mediastinitis: classification and management. Ann Thorac Surg 61:1030–1036

    Article  PubMed  CAS  Google Scholar 

  90. Milano CA, Kesler K, Archibald N (1995) Mediastinitis after coronary artery bypass graft surgery. Risk factors and long-term survival. Circulation 92:2245–2251

    PubMed  CAS  Google Scholar 

  91. Brook I, Frazier EH (1996) Microbiology of mediastinitis. Arch Intern Med 156:333–336

    Article  PubMed  CAS  Google Scholar 

  92. Shaffer HA Jr, Valenzuela G, Mittal RK (1992) Esophageal perforation. A reassessment of the criteria for choosing medical or surgical therapy. Arch Intern Med 152:757–761

    Article  PubMed  Google Scholar 

  93. Loop FD, Lytle BW, Cosgrove DM (1990) J Maxwell Chamberlain memorial paper. Sternal wound complications after isolated coronary artery bypass grafting: early and late mortality, morbidity, and cost of care. Ann Thorac Surg 49:179–187

    Article  PubMed  CAS  Google Scholar 

  94. Gadek JE, DeMichele SJ, Karlstad MD (1999) Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Enteral nutrition in ARDS study group. Crit Care Med 27:1409–1420

    Article  PubMed  CAS  Google Scholar 

  95. Weinzweig N, Yetman R (1995) Transposition of the greater omentum for recalcitrant median sternotomy wound infections. Ann Plast Surg 34:471–477

    Article  PubMed  CAS  Google Scholar 

  96. Andrews CO, Gora ML (1994) Pleural effusions: pathophysiology and management. Ann Pharmacother 28:894–903

    PubMed  CAS  Google Scholar 

  97. Bartter T, Santarelli R, Akers SM (1994) The evaluation of pleural effusion. Chest 106:1209–1214

    Article  PubMed  CAS  Google Scholar 

  98. Fenton KN, Richardson JD (1995) Diagnosis and management of malignant pleural effusions. Am J Surg 170:69–74

    Article  PubMed  CAS  Google Scholar 

  99. Kennedy L, Sahn SA (1994) Noninvasive evaluation of the patient with a pleural effusion. Chest Surg Clin N Am 4:451–465

    PubMed  CAS  Google Scholar 

  100. Light RW (1995) Pleural diseases, 3rd edn. Williams & Wilkins, New York

    Google Scholar 

  101. Sahn SA (1988) State of the art. The pleura. Am Rev Respir Dis 138:184–234

    Article  PubMed  CAS  Google Scholar 

  102. Sganga G, Brisinda G, Castagneto M (2001) Practical aspects of antibiotic prophylaxis in high-risk surgical patients. In: van Saene HKF, Sganga G, Silvestri L (eds) Infection in the critically ill: an ongoing challenge. Springer, Berlin, pp 47–58

    Google Scholar 

  103. Mangram AJ, Horan TC, Pearson ML et al (1996) The hospital infection control practices advisory committee. Guideline for the prevention of surgical site infection. Infect Control Hosp Epidemiol 20:247–280

    Google Scholar 

  104. Sganga G, Cozza V (2009) Intra-abdominal infections: diagnostic and surgical strategies. In: Gullo A, Besso J, Lumb PD, Williams GF (eds) Intensive and critical care medicine. (WFSICCM) World federation of societies of intensive and critical care medicine. Springer, Milan, pp 315–324

    Google Scholar 

  105. Kurz A, Sessler DI, Lenhardt R (1996) Perioperative normothermia to reduce the incidende of surgical-wound infection and shorten hospitalization. N Engl J Med 334:1209–1215

    Article  PubMed  CAS  Google Scholar 

  106. Classen DC, Evans RS, Pestotnik A (1992) The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection. N Engl J Med 326:281–287

    Article  PubMed  CAS  Google Scholar 

  107. Nathens AB, Marshall JC (1999) Selective decontamination of the digestive tract in surgical patients. A systematic review of the evidence. Arch Surg 134:170–176

    Article  PubMed  CAS  Google Scholar 

  108. Silvestri L, Mannucci F, van Saene HKF (2000) Selective decontamination of the digestive tract: a life-saver. J Hosp Infect 45:185–190

    Article  PubMed  CAS  Google Scholar 

  109. van Saene HKF, Silvestri L, de la Cal M (2000) Prevention of nosocomial infections in the intensive care unit. Curr Opin Crit Care 6:323–329

    Article  Google Scholar 

  110. Greif R, Akca O, Horn EP et al (2000) Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med 342:161–167

    Article  PubMed  CAS  Google Scholar 

  111. Jancel T, Dudas V (2002) Management of uncomplicated urinary tract infections. West J Med 176:51–55

    Article  PubMed  Google Scholar 

  112. Larcombe J (1999) Urinary tract infection in children. BMJ 319:1173–1175

    Article  PubMed  CAS  Google Scholar 

  113. Ellis AK, Verma S (2000) Quality of life in women with urinary tract infections: is benign disease a misnomer? J Am Board Fam Pract 13:392–397

    PubMed  CAS  Google Scholar 

  114. Hooten TM, Scholes D, Stapleton AE (2000) A prospective study of asymptomatic bacteriuria in sexually active young women. N Engl J Med 343:992–997

    Article  Google Scholar 

  115. Howes DS, Young WF (2000) Urinary tract infections. In: Tintinalli A (ed) Emergency medicine. A comprehensive study guide. McGraw-Hill, New York, pp 625–631

    Google Scholar 

  116. Leibovici L, Greenshtain S, Cohen O, Wysenbeek AJ (1992) Toward improved empiric management of moderate to severe urinary tract infections. Arch Intern Med 152:2481–2486

    Article  PubMed  CAS  Google Scholar 

  117. Millar LK, Wing DA, Paul RH, Grimes DA (1995) Outpatient treatment of pyelonephritis in pregnancy: a randomized controlled trial. Obstet Gynecol 86:560–564

    PubMed  CAS  Google Scholar 

  118. Safrin S, Siegel D, Black D (1988) Pyelonephritis in adult women: inpatient versus outpatient therapy. Am J Med 85:793–798

    Article  PubMed  CAS  Google Scholar 

  119. Stamm WE, Hooton TM (1993) Management of urinary tract infections in adults. N Engl J Med 329:1328–1334

    Article  PubMed  CAS  Google Scholar 

  120. Foxman B, Barlow R, D’Arcy H et al (2000) Urinary tract infection: self-reported incidence and associated costs. Ann Epidemiol 10:509–515

    Article  PubMed  CAS  Google Scholar 

  121. Manges AR, Johnson JR, Foxman B et al (2001) Widespread distribution of urinary tract infections caused by a multidrug-resistant Escherichia coli clonal group. N Engl J Med 345:1007–1013

    Article  PubMed  CAS  Google Scholar 

  122. Stark RP, Maki DG (1984) Bacteriuria in the catheterized patient. N Engl J Med 311:560–564

    Article  PubMed  CAS  Google Scholar 

  123. Trautner BW, Darouiche RO (2004) Catheter-associated infections. Arch Intern Med 164:842–850

    Article  PubMed  Google Scholar 

  124. Lo E, Lindsay N, Classen D et al (2008) Strategies to prevent catheter-associated urinary tract infections in acute care hospitals. Infect Control Hosp Epidemiol 29:S41–S50

    Article  PubMed  Google Scholar 

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Sganga, G., Brisinda, G., Cozza, V., Castagneto, M. (2011). Infections of Peritoneum, Mediastinum, Pleura, Wounds, and Urinary Tract. In: van Saene, H., Silvestri, L., de la Cal, M., Gullo, A. (eds) Infection Control in the Intensive Care Unit. Springer, Milano. https://doi.org/10.1007/978-88-470-1601-9_16

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