Abstract
Intra-abdominal infections (IAIs) are defined as an inflammatory response of the peritoneum to microorganisms and their toxins, which results in purulent exudate in the abdominal cavity. They have two major manifestations: generalized peritonitis and IA abscess. Mortality rates for peritonitis, regardless of diagnostic and therapeutic developments in recent years, remain unacceptably high and still represent one of the greatest challenges for surgeons. Drainage, debridement, and definitive surgical management are the usual consecutive steps to be carried out, but in many circumstances, the procedure has to be tailored to the individual patient. Successful source control and antibiotic management is associated with illness resolution. Progression or failure to resolve organ dysfunction suggests disease persistence and the need for further intervention. Particular interest has been given to severe acute pancreas and its diagnosis and management, as well as to mediastinitis and pleural infection disease. Furthermore, we discuss the two most important sources of infection in surgery: wound and urinary tract.
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Sganga, G., Brisinda, G., Cozza, V., Castagneto, M. (2011). Infections of Peritoneum, Mediastinum, Pleura, Wounds, and Urinary Tract. In: van Saene, H., Silvestri, L., de la Cal, M., Gullo, A. (eds) Infection Control in the Intensive Care Unit. Springer, Milano. https://doi.org/10.1007/978-88-470-1601-9_16
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