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Tecniche per l’analisi dei polimorfismi

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Introduzione alla genetica forense

Riassunto

L’ideazione e la pubblicazione nel 1985 della tecnica della reazione a catena della polimerasi (Polymerase Chain Reaction, PCR) da parte di Kary Mullis e dei membri dello Human Genetics Group della Cetus Corporation ha rivoluzionato la biologia molecolare. Le scienze forensi hanno tratto grandi benefici dallo sviluppo di questa nuova tecnica, in grado di produrre milioni di copie di una specifica sequenza di DNA in poche ore; poiché infatti il materiale genetico rinvenibile sulla scena del crimine è spesso scarso sia in quantità che in qualità, sarebbe stato impossibile analizzare molti campioni forensi prima di questa innovazione.

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Onori, N. (2010). Tecniche per l’analisi dei polimorfismi. In: Introduzione alla genetica forense. Springer, Milano. https://doi.org/10.1007/978-88-470-1512-8_5

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