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Polymer Based Biointerfaces: A Case Study on Devices for Theranostics and Tissue Engineering

  • Pamela Mozetic
  • Mariarosaria Tortora
  • Barbara Cerroni
  • Gaio Paradossi

Abstract

In the design of new devices supporting biomedical applications, the focus on the processes occurring at the interface with cells is a major issue. In this context, our interest on the formulation of new biomaterials and on the synthesis of next-generation ultrasound contrast agents (UCAs) lead us to the in vitro study to assess the biocompatibility of these novel devices. As UCAs are designed for parenteral administration, the time response of the primary immune system, mainly macrophages, should be addressed.

Keywords

Nitric Oxide Confocal Laser Scanning Microscopy Ultrasound Contrast Agent Membrane Hydrogel Multifunctional Device 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Barretta P, Bordi F, Rinaldi C and Paradossi G (2000) A Dynamic Light Scattering Study of Hydrogels Based on Telechelic PVA. J Phys Chem B 104:11019–11026CrossRefGoogle Scholar
  2. 2.
    Cavalieri F, El-Hamassi A, Chiessi E and Paradossi G (2005) Stable polymeric microballoons as multifunctional device for biomedical uses: synthesis and characterization. Langmuir 21:8758–8764CrossRefGoogle Scholar
  3. 3.
    Cavalieri F, Finelli I, Tortora M, Mozetic P, Chiessi E, Polizio F, Brismar TB and Paradossi G (2008) Polymer Microballoons As Diagnostic and Therapeutic Gas Delivery Device. Chem Mater 2:3254–3258CrossRefGoogle Scholar
  4. 4.
    Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of immunological methods 65:55–63CrossRefGoogle Scholar
  5. 5.
    Ruoslahti E (1996) RGD and other recognition sequences for integrins. Ann Rev Cell Dev Biol 12:697–715CrossRefGoogle Scholar
  6. 6.
    Stoscheck CM (1990) Quantitation of Protein. Methods in Enzym 182:50–69CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 2010

Authors and Affiliations

  • Pamela Mozetic
    • 1
  • Mariarosaria Tortora
    • 1
  • Barbara Cerroni
    • 1
  • Gaio Paradossi
    • 1
  1. 1.Dipartimento di Scienze e Tecnologie ChimicheUniversità di Roma Tor VergataRomaItaly

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