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Problema: malattie prostatiche (infezione, ipertrofia benigna e cancro della prostata)

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Andrologia clinica

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L’ipertrofia benigna della prostata (Benign Prostatic Hyperplasia, BPH) e il cancro della prostata sono due malattie distinte che comunemente colpiscono la prostata degli uomini nella fase dell’invecchiamento. La prostata è una ghiandola sessuale accessoria, situata intorno all’uretra alla base della vescica, le cui dimensioni aumentano dopo la pubertà sotto l’influenza del testosterone. I tessuti ghiandolari della prostata sono organizzati in tre zone, come descritto da McNeal (1981,1988). Queste affezioni hanno la tendenza a colpire parti differenti della ghiandola. La BPH colpisce quasi esclusivamente la zona di transizione della prostata che circonda l’uretra. Benché possa anche sopraggiungere nelle zone centrali e di transizione, il cancro della prostata interessa il più delle volte la zona periferica della ghiandola, ragione per la quale l’esplorazione rettale (Digital Rectal Examination, DRE) è molto utile alla valutazione della prostata. Poiché queste malattie colpiscono di preferenza regioni distinte, non sorprende che la BPH tenda a presentarsi con sintomi legati all’ostruzione urinaria più precocemente del cancro della prostata, mentre i pazienti che presentano sintomi di ostruzione urinaria per cancro della prostata saranno spesso a uno stadio avanzato della malattia (Fig. 1.9.1).

Anatomia regionale della prostata

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Authors and Affiliations

  1. Department of Urology, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK

    S. Alan McNeill

  2. Prostate Research Group, School of Molecular and Clinical Medicine, The University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh, EH4 2XU, UK

    Steve Ken Wing Leung

  3. Department of Urology, Nottingham City Hospital NHS Trust, Nottingham, NG5 1 PB, UK

    M. C. Bishop

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  1. S. Alan McNeill
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Editors and Affiliations

  1. Center of Dermatology and Andrology, Justus Liebig University, Giessen, Germany

    Wolf-Bernhard Schill

  2. Center for Medical and Urological Andrology and Reproductive Endocrinology, University Hospital, Ghent, Belgium

    Frank Comhaire

  3. Department of Oncology, University of Edinburgh Human Genetics Building, Western General Hospital, Edinburgh, Scotland, UK

    Timothy B. Hargreave

  4. Dipartimento di Fisiopatologia Medica, “Sapienza” Università di Roma, Roma, Italy

    Andrea Lenzi MD (Professore Ordinario di Endocrinologia Direttore, Presidente della Società Italiana di Andrologia e Medicina della Sessualità) (Professore Ordinario di Endocrinologia Direttore, Presidente della Società Italiana di Andrologia e Medicina della Sessualità)

  5. Unità di Fisiopatologia della Riproduzione, Andrologia e Diagnosi Endocrinologiche Dipartimento di Fisiopatologia Medica, “Sapienza” Università di Roma, Roma, Italy

    Andrea M. Isidori MD, PhD (Ricercatore in Endocrinologia) (Ricercatore in Endocrinologia)

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McNeill, S.A., Leung, S.K.W., Bishop, M.C. (2010). Problema: malattie prostatiche (infezione, ipertrofia benigna e cancro della prostata). In: Schill, WB., Comhaire, F., Hargreave, T.B., Lenzi, A., Isidori, A.M. (eds) Andrologia clinica. Springer, Milano. https://doi.org/10.1007/978-88-470-1487-9_15

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  • DOI: https://doi.org/10.1007/978-88-470-1487-9_15

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