Endoscopy and Surgical Oncology

  • Claudio De Angelis
  • Alessandro Repici
  • Matteo Goss
Part of the Updates in Surgery book series (UPDATESSURG)


Endoscopic therapy has emerged as a highly effective and minimally invasive way to control and cure early neoplasia of the digestive tract. Polypectomy has been a major advance, and most recently ablation and endoscopic mucosal resection seem to be highly successful in treating flat neoplastic areas involving the gut mucosa. The use of endoscopic ultrasonography (EUS) has resulted in improved accuracy for cancer staging, and EUS-guided fine-needle aspiration has been successful in obtaining tissue diagnosis outside the gut lumen. In advanced cancer, usually managed by multidisciplinary teams of oncologists, surgeons, and radiologists, the gastrointestinal endoscopist (GI) has assumed a key role not only in diagnosis but in palliation with the use of stents to bridge GI obstruction, ablation and the placement of tubes for drainage and feeding.


Endoscopic Submucosal Dissection Early Gastric Cancer Endoscopic Mucosal Resection Bloc Resection Argon Plasma Coagulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Ishiguro A, Uno Y, Ishiguro Y et al (1999) Correlation of lifting versus non-lifting and microscopic depth of invasion in early colorectal cancer. Gastrointest Endosc 50:329–333CrossRefPubMedGoogle Scholar
  2. 2.
    Uno Y, Munakata A (1994) The non-lifting sign of invasive colon cancer. Gastrointest Endosc 40:485–489PubMedGoogle Scholar
  3. 3.
    Tada M (2001) Endoscopic mucosal resection of the stomach: initial description. Gastrointest Endosc Clin N Am 11:499–510PubMedGoogle Scholar
  4. 4.
    Kanamori T, Itoh M, Yokoyama Y et al (1996) Injection-incision-assisted snare resection of large sessile colorectal polyps. Gastrointest Endosc 43:189–195CrossRefPubMedGoogle Scholar
  5. 5.
    Clark G, Peters J, Ireland A et al (1994) Nodal metastasis and sites of recurrence after en bloc esophagectomy for adenocarcinoma. Ann Thorac Surg 58:646–653PubMedCrossRefGoogle Scholar
  6. 6.
    Yamao T, Shirao K, Ono H et al (1996) Risk factors for lymph node metastasis from intramucosal gastric carcinoma. Cancer 77:602–606CrossRefPubMedGoogle Scholar
  7. 7.
    Takekoshi T, Baba Y, Ota H et al (1994) Endoscopic resection of early gastric carcinoma: results of a retrospective analysis of 308 cases. Endoscopy 26:352–358CrossRefPubMedGoogle Scholar
  8. 8.
    Makuuchi H, Kise Y, Shimada H et al (1999) Endoscopic mucosal resection for early gastric cancer. Semin Surg Oncol 17:108–116CrossRefPubMedGoogle Scholar
  9. 9.
    Tanaka S, Haruma K, Oka S et al (2001) Clinicopathologic features and endoscopic treatment of superficially spreading colorectal neoplasms larger than 20 mm. Gastrointest Endosc 54:62–66CrossRefPubMedGoogle Scholar
  10. 10.
    Kim MH, Lee SK, Seo DW et al (2001) Tumors of the major duodenal papilla. Gastrointest Endosc 54:609–620CrossRefPubMedGoogle Scholar
  11. 11.
    Binmoeller KF, Boaventura S, Ramsperger K et al (1993) Endoscopic snare excision of benign adenomas of the papilla of Vater. Gastrointest Endosc 39:127–131CrossRefPubMedGoogle Scholar
  12. 12.
    Dormann A, Meisner S, Verin N et al (2004) Self-expanding metal stents for gastroduodenal malignancies: systematic review of their clinical effectiveness. Endoscopy 36:543–550CrossRefPubMedGoogle Scholar
  13. 13.
    Pungpapong S, Raimondo M, Wallace MB et al (2004) Problematic esophageal strictures: emerging indications for self-expandable silicone stents. Am J Gastroenterol 99:AB363Google Scholar
  14. 14.
    Baron TH (2001) Expandable metal stents for the treatment of cancerous obstruction of the gastrointestinal tract. N Engl J Med 344:1681–1687CrossRefPubMedGoogle Scholar
  15. 15.
    Adler DG, Young-Fadok TM, Smyrk T et al (2002) Preoperative chemoradiation therapy after placement of a self-expanding metal stent in a patient with an obstructing rectal cancer: clinical and pathologic findings. Gastrointest Endosc 55:435–437CrossRefPubMedGoogle Scholar
  16. 16.
    Tajiri H, Matsuda K, Fujisaki J (2002) What can we see with the endoscope? Present status and future perspectives. Dig Endosc 14:131–137CrossRefGoogle Scholar
  17. 17.
    Kara MA, Peters FP, Rosmolen WD et al (2005) High-resolution endoscopy plus chromoendoscopy or narrow-band imaging in Barrett’s esophagus: a prospective randomized crossover study. Endoscopy 37:929–936CrossRefPubMedGoogle Scholar
  18. 18.
    Sambongi M, Igarashi M, Obi T et al (2000) Analysis of spectral reflectance of mucous membrane for endoscopic diagnosis. Med Phys 27:1396–1398Google Scholar
  19. 19.
    Kiesslich R, Jung M (2002) Magnification endoscopy: does it improve mucosal surface analysis for the diagnosis of gastrointestinal neoplasias? Endoscopy 34:819–822CrossRefPubMedGoogle Scholar
  20. 20.
    Sharma P, Weston AP, Topalovski M et al (2003) Magnification chromoendoscopy for the detection of intestinal metaplasia and dysplasia in Barret’s oesophagus. Gut 52:24–27CrossRefPubMedGoogle Scholar
  21. 21.
    No authors listed (2005) Paris workshop on columnar metaplasia in the esophagus and the esophagogastric junction. Paris, France, December 11–12, 2004. Endoscopy 37:879–920Google Scholar
  22. 22.
    Kuznetsov K, Lambert R, Rey J-F (2006) Narrow-band imaging: potential and limitations. Endoscopy 38:76–81CrossRefPubMedGoogle Scholar
  23. 23.
    Lambert R and the Endoscopic Classification Review Group (2005) Update on the Paris classification of superficial neoplastic lesions in the digestive tract. Endoscopy 37:570–578CrossRefGoogle Scholar
  24. 24.
    Yasuda K, Mukai H, Nakajima M (1992) Clinical application of ultrasonic probes in the biliary and pancreatic duct. Endoscopy 24(Suppl 1):370–375CrossRefPubMedGoogle Scholar
  25. 25.
    De Angelis C, Martini M, Repici A et al (2007) Instruments and accessories for diagnostic endoscopic ultrasound (radial scanning and miniprobes). Minerva Med 98:253–260PubMedGoogle Scholar
  26. 26.
    Hasegawa N, Niwa Y, Arisawa T et al (1996) Preoperative staging of superficial esophageal carcinoma: comparison of an ultrasound probe and standard endoscopic ultrasonography. Gastrointest Endosc 44:388–393CrossRefPubMedGoogle Scholar
  27. 27.
    Waxman I, Saitoh Y, Raju GS et al (2002) High-frequency probe EUS-assisted endoscopic mucosal resection: a therapeutic strategy for submucosal tumors of the GI tract. Gastrointest Endosc 55:44–49CrossRefPubMedGoogle Scholar
  28. 28.
    Yasuda K, Mukai H, Nakajima M (1995) Endoscopic ultrasonography diagnosis of pancreatic cancer. Gastrointest Endosc Clin N Am 5:699–712PubMedGoogle Scholar
  29. 29.
    De Angelis C, Repici A, Carucci P et al (2007) Pancreatic cancer imaging; the new role of endoscopic ultrasound. JOP 8(Suppl I):85–97PubMedGoogle Scholar
  30. 30.
    De Angelis C, Senore C, Ciccone G et al (2005) Accuracy of endoscopic ultrasound guided fine needle aspiration (FNA) in the diagnosis of solid pancreatic masses: a systematic review of the literature. Endoscopy 37(Suppl I):A282–283Google Scholar

Copyright information

© Springer-Verlag Italia 2010

Authors and Affiliations

  • Claudio De Angelis
    • 1
  • Alessandro Repici
    • 2
  • Matteo Goss
    • 3
  1. 1.Echoendoscopy Service and GEP Neuroendocrine Tumors Center, Department of Gastro HepatologyS. Giovanni Battista University HospitalTurinItaly
  2. 2.Digestive Endoscopy UnitIRCCS Istituto Clinico HumanitasMilanItaly
  3. 3.Surgical Oncology UnitS. Giovanni Battista University HospitalTurinItaly

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