Prosthetic Materials in Surgical Oncology

  • Flavio Trombetta
  • Tommaso Lubrano
Part of the Updates in Surgery book series (UPDATESSURG)


The use of prostheses in surgery is nowadays widespread, though some doubts still remain on the hypothetical carcinogenicity of these prostheses. Some investigational trials have shown the possibility of carcinogenic stimulation by foreign bodies introduced into the body, like those by Vasiliev and Moizhess in 1982 [1], where polyvinyl hydrochloride film was inserted into the abdomen of some rats and some sarcomatous cells were subsequently introduced. It was then possible to observe an increase in the rate and decrease in growth times of sarcomas thus induced.


Foreign Body Hernia Repair Inguinal Hernia Incisional Hernia Radical Cystectomy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Vasiliev JuM, Moizhess TG (1982) Tumorigenicity of sarcoma cells is enhanced by the local environment of implanted foreign body. Int J Cancer. 30:525–529CrossRefPubMedGoogle Scholar
  2. 2.
    Brand KG, Buoen LC, Johnson KH, Brand I (1975) Etiological factors, stages, and the role of the foreign body in foreign body tumorigenesis: a review. Cancer Res 35:279–286PubMedGoogle Scholar
  3. 3.
    Jennings TA, Peterson L, Axiotis CA et al (1988) Angiosarcoma associated with foreign body material. A report of three cases. Cancer 62:2436–2444CrossRefPubMedGoogle Scholar
  4. 4.
    Ghadimi BM, Langer C, Becker H (2002) The carcinogenic potential of biomaterials in hernia surgery. Chirurg 73:833–837CrossRefPubMedGoogle Scholar
  5. 5.
    Imai M, Kondo Y, Masuko H et al (2003) Distant peritoneal metastasis to a mesh-plug prosthesis in a gastrointestinal cancer patient: report of a case. Surg Today 33:864–866CrossRefPubMedGoogle Scholar
  6. 6.
    Gray MW, Caleel RT, Sorg RJ (1996) Soft tissue sarcoma of the anterior abdominal wall: review of reconstruction techniques. J Am Osteopath Assoc 96:48–53PubMedGoogle Scholar
  7. 7.
    Puppo P, Introini C, Calvi P, Naselli A (2005) Pelvic floor reconstruction before orthotopic bladder replacement after radical cystectomy for bladder cancer. Urology 65:174CrossRefPubMedGoogle Scholar
  8. 8.
    Olejek A (2006) Use of prolene mesh in surgical treatment of tissue defects after radical inguinal and pelvic lymph node dissection in vulvar cancer—a brief report. Int J Gynecol Cancer 16:448–451CrossRefPubMedGoogle Scholar
  9. 9.
    Akan M, Eker Uluçay G, Kargi B et al (2006) Combined reconstruction of complex defects of the chest wall. Scand J Plast Reconstr Surg Hand Surg 40:93–100CrossRefPubMedGoogle Scholar
  10. 10.
    Haraguchi S, Hioki M, Hisayoshi T et al (2006) Resection of sternal tumors and reconstruction of the thorax: a review of 15 patients. Surg Today 36:225–229CrossRefPubMedGoogle Scholar
  11. 11.
    Haraguchi S, Hioki M, Hisayoshi T et al (2006) Resection of sternal metastasis from endometrial carcinoma followed by reconstruction with sandwiched marlex and stainless steel mesh: report of a case. Surg Today 36:184–186CrossRefPubMedGoogle Scholar
  12. 12.
    Murphy F, Corbally MT (2007) The novel use of small intestinal submucosal matrix for chest wall reconstruction following Ewing’s tumor resection. Pediatr Surg Int 23:353–356CrossRefPubMedGoogle Scholar
  13. 13.
    Rettenmaier MA, Goldstein BH, Micha JP, Brown JV (2006) Vaginal reconstruction following supra-levator total pelvic exenteration. Gynecol Oncol 102:397–399CrossRefPubMedGoogle Scholar
  14. 14.
    Adell-Carceller R, Segarra-Soria MA, Pellicer-Castell V et al (2006) Incisional hernia in colorectal cancer surgery. Associated risk factors. Cir Esp 79:42–45CrossRefPubMedGoogle Scholar
  15. 15.
    Franchi M, Ghezzi F, Buttarelli M et al (2001) Incisional hernia in gynecologic oncology patients: a 10-year study. Obstet Gynecol 97:696–700CrossRefPubMedGoogle Scholar
  16. 16.
    Shaikh FM, Giri SK, Durrani S et al (2007) Experience with porcine acellular dermal collagen implant in one-stage tension-free reconstruction of acute and chronic abdominal wall defects. World J Surg 31:1966–1972CrossRefPubMedGoogle Scholar
  17. 17.
    Trombetta F, Tonda-Turo C, Tori A (2008) Light-and heavy-weight meshes: comparison of two concepts. Osp Ital Chir 14:88–94Google Scholar
  18. 18.
    Kingsnorth AN, Shahid MK, Valliattu AJ et (2008) Open onlay mesh repair for major abdominal wall hernias with selective use of components separation and fibrin sealant. World J Surg 32:26–30CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia 2010

Authors and Affiliations

  • Flavio Trombetta
    • 1
  • Tommaso Lubrano
    • 1
  1. 1.Surgical Oncology UnitS. Giovanni Battista University HospitalTurinItaly

Personalised recommendations