Crohn’s disease (CD) potentially affects many organs, including, albeit rarely, the kidney. The most frequent renal manifestations are calcium oxalate stones and their complications; secondary amyloidosis; acute tubular necrosis related to volume depletion caused by diarrheal fluid losses or inadequate fluid intake, or both. Tubulo-interstitial nephritis is another common finding and, among patients with CD, the most common cause is drug-related nephritis. However, case reports in the literature suggest that granulomatous interstitial nephritis is also an extraintestinal manifestation of CD. Glomerulonephritis has been reported in CD patients as well.
KeywordsFamilial Mediterranean Fever Interstitial Nephritis Systemic Amyloidosis Acute Interstitial Nephritis Extraintestinal Manifestation
Unable to display preview. Download preview PDF.
- 6.Viana ML, Pontes RM, Garcia WE et al (2007) Crohn’s disease and kidney stones: much more than coincidence? Arch Gastroenterol 44:210–214Google Scholar
- 7.National Kidney Disease Education Program. Information of Health Professionals 2006 Creatinine Standardization Program. Accessed at http://www.nkdep.nih.gov/professionals/gfr_calculators/index.htmGoogle Scholar
- 8.National Kidney Foundation (2002) K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Kidney Disease Outcome Quality Initiative. Am J Kidney Dis 39:S1–266Google Scholar