Rheumatological Manifestations of Crohn’s Disease

  • Giovanni Minisola
  • Giuseppe Famularo
Part of the Updates in Surgery book series (UPDATESSURG)


The correlation between inflammatory bowel disease (IBD) and articular involvement has long been well known, but a nosographic classification was proposed only in the early 1970s, when two clinical forms of chronic intestinal inflammation were identified: Crohn’s disease (CD) and ulcerative colitis (UC). Both conditions were considered to be responsible for the peculiar forms of arthritis seen in a subset of patients with seronegative spondyloarthritides (SnSp) (Fig. 18.1) [1]. Numerous clinical and experimental findings subsequently drew strong attention to the enormous relevance of the relationship between IBD and either axial or peripheral articular inflammations [2,3].
Fig. 18.1

Linical conditions belonging to the group of seronegative spondyloarthritides (SnSp). IBD. inflammatory bowel disease: SAPHO, synovitis, acne, pustulosis, hyperostosis, osteitis


Inflammatory Bowel Disease Ankylose Spondylitis Sacroiliac Joint Joint Involvement Intestinal Disease 
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Copyright information

© Springer-Verlag Italia 2010

Authors and Affiliations

  • Giovanni Minisola
    • 1
  • Giuseppe Famularo
    • 2
  1. 1.Rheumatology UnitSan Camillo-Forlanini HospitalRomeItaly
  2. 2.Department of Internal MedicineSan Camillo-Forlanini HospitalRomeItaly

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