Intra-Abdominal Infections: Diagnostic and Surgical Strategies

  • G. Sganga
  • V. Cozza


Intra-abdominal infections (IAIs) are defined as an inflammatory response of the peritoneum to micro-organisms and their toxins, which results in purulent exudate in the abdominal cavity [1, 2, 3, 4, 5]. They have two major manifestations: generalized peritonitis and IA abscess. Peritonitis remains a potentially fatal disease and still represents a challenge for surgeons [3]. Although greater understanding of the pathophysiology of IAIs, improvement in critical care, and timely surgical and/or radiological intervention have reduced the mortality associated with severe peritonitis, the rate remains unacceptably high, ranging from 3% in localized abscess to 10% in localized peritonitis, 32% in diffuse suppurative peritonitis, and 70–80% in complicated mixed infections [1, 2, 3, 4, 5]. In an effort to improve the results of treatment of severe IAIs, especially of those resulting from anastomotic leakage or perforation of the gastrointestinal tract (GIT), new surgical techniques have been introduced.


Abdominal Compartment Syndrome Source Control Spontaneous Bacterial Peritonitis Intraabdominal Infection Secondary Peritonitis 
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Copyright information

© Springer-Verlag Italia 2009

Authors and Affiliations

  • G. Sganga
    • 1
  • V. Cozza
    • 1
  1. 1.Department of Surgery, Istituto Clinica ChirurgicaCatholic University, Policlinico A. GemelliRomeItaly

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