Selective Decontamination of the Digestive Tract (SDD). Twenty-five Years of European Experience

  • L. Silvestri
  • M. A. de la Cal
  • H. K. F. van Saene


The key to infection control in the intensive care unit (ICU) is to appreciate that three different types of infection, due to a limited range of potentially pathogenic micro-organisms (PPMs), six “normal” and nine “abnormal,” require a different prophylactic maneuver. Primary endogenous infections can only be controlled by the immediate administration of parenteral antibiotics, and secondary endogenous infections by the application of enteral antimicrobials in throat and gut. A high level of hygiene and topical antimicrobials are required to control exogenous infections despite being less frequent [1, 2, 3] (Table 23.1).


Intensive Insulin Therapy Selective Digestive Decontamination Tight Glucose Control Selective Decontamination Selective Oropharyngeal Decontamination 
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Copyright information

© Springer-Verlag Italia 2009

Authors and Affiliations

  • L. Silvestri
    • 1
    • 2
  • M. A. de la Cal
    • 3
  • H. K. F. van Saene
    • 4
    • 5
  1. 1.Department of Anesthesia and Intensive CarePresidio Ospedaliero di GoriziaGoriziaItaly
  2. 2.Peep TalvingUniversity of Southern CaliforniaLos AngelesUSA
  3. 3.Intensive Care UnitHospital Universitario de GetafeGetafe (Madrid)Spain
  4. 4.School of Clinical SciencesUniversity of LiverpoolLiverpoolUK
  5. 5.Department of Medical MicrobiologyUniversity of LiverpoolLiverpoolUK

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