Infections in ICU: An Ongoing Challenge

  • H. K. F. van Saene
  • D. F. Zandstra
  • A. J. Petros
  • L. Silvestri
  • A. R. De Gaudio


During the late 1970s most intensivists acknowledged that the pathogenesis of the majority of infections in the intensive care unit (ICU) was endogenous. However, there were no supporting data.


Selective Decontamination Selective Oropharyngeal Decontamination Exogenous Infection Subglottic Secretion Drainage Oral Decontamination 
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Copyright information

© Springer-Verlag Italia 2009

Authors and Affiliations

  • H. K. F. van Saene
    • 1
    • 2
  • D. F. Zandstra
    • 3
  • A. J. Petros
    • 4
  • L. Silvestri
    • 5
    • 6
  • A. R. De Gaudio
    • 7
  1. 1.School of Clinical SciencesUniversity of LiverpoolLiverpoolUK
  2. 2.Department of Medical MicrobiologyUniversity of LiverpoolLiverpoolUK
  3. 3.Intensive Care Unit OLVGAmsterdamThe Netherlands
  4. 4.Intensive Care UnitGreat Ormond Street Hospital for ChildrenLondonUK
  5. 5.Department of Anesthesia and Intensive CarePresidio Ospedaliero di GoriziaGoriziaItaly
  6. 6.Peep TalvingUniversity of Southern CaliforniaLos AngelesUSA
  7. 7.Department of Critical Care, Section of Anesthesiology and Intensive CareUniversity of FlorenceFlorenceItaly

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