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ALI, ARDS, and Protective Lung Ventilation

  • R. Nanchal
  • E. J. Jimenez
  • F. E. Poalillo

Abstract

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are clinical syndromes characterized by acute onset of severe hypoxemia and diffuse bilateral pulmonary infiltrates in the absence of clinical evidence of left heart failure. The mainstay of treatment is supportive care with an emphasis on the delivery of mechanical ventilation. Often these syndromes are a part of a systemic critical illness, such as severe sepsis, polytrauma, or multiple organ failure with injury to the lung, either directly or indirectly. Increasingly, recognition of the genetic predisposition to lung injury has enhanced our understanding about these syndromes. Though therapeutic options are limited, evidence from prospective randomized trials over the last decade has provided insights into mechanical ventilation and fluid management strategies for these patients, which have improved mortality and decreased ventilator days.

Keywords

Acute Lung Injury Acute Respiratory Distress Syndrome Respir Crit Recruitment Maneuver Diffuse Alveolar Damage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2009

Authors and Affiliations

  • R. Nanchal
    • 1
  • E. J. Jimenez
    • 2
    • 3
  • F. E. Poalillo
    • 4
  1. 1.Medical Intensive Care Unit, Division of Pulmonary and Critical Care MedicineMedical College of WisconsinMilwaukeeUSA
  2. 2.Central Florida and Florida State UniversityUniversities of FloridaOrlandoUSA
  3. 3.Critical Care and Intermediate Critical CareOrlando Regional Medical CenterOrlandoUSA
  4. 4.Intensive Care UnitsOrlando Regional Medical CenterOrlandoUSA

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