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Thyroid

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Fine-Needle Biopsy of Superficial and Deep Masses

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Abstract

Fine-needle biopsy (FNB) is the most effective and efficient diagnostic procedure to study thyroid nodular lesions [1–9]. It is inexpensive, rapidly performed, very well-tolerated by the patient in any context, and immediately repeatable. In experienced hands, FNB is highly reliable in the diagnosis of benign lesions and in the identification and typing of a significant number of malignant tumors. Since the predictive value of a negative diagnosis is very high, the patient can be confidently assured and followed up unless other clinical conditions or risk factors warrant a more aggressive approach. The positive predictive value of the procedure is similarly high and the most appropriate oncological therapy can be started immediately after a FNB diagnosis of malignancy. There are, however, a few cases in which the diagnosis remains inevitably indeterminate in terms of possible malignancy [2,10]. These fall into the diagnostic category “follicular proliferation” and account for about 10–30% of cases in most series [2,10,11–14].

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Authors and Affiliations

  1. Institute of Anatomic Pathology and Cytopathology, Fatebenefratelli Hospital, Milan, Italy

    Giorgio Gherardi MD (Head, Professor)

  2. Postgraduate School of Anatomic Pathology, University of Milan, Italy

    Giorgio Gherardi MD (Head, Professor)

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Gherardi, G. (2009). Thyroid. In: Fine-Needle Biopsy of Superficial and Deep Masses. Springer, Milano. https://doi.org/10.1007/978-88-470-1433-6_3

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