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Surgical Treatment of Mitral Regurgitation and Aortic Stenosis

  • Corrado Tamburino
  • Gian Paolo Ussia

Abstract

The most important objective of modern mitral surgery is to “neutralize” this disease and hence not just correct the valve defect, but also achieve a life expectancy in line with that of the healthy population with normal cardiac function. Disease neutralization is a target that can only be realistically achieved in degenerative mitral regurgitation (MR).

Keywords

Mitral Valve Aortic Stenosis Mitral Regurgitation Mitral Valve Repair Mitral Valve Prolapse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Savage DD, Garrison RJ, Devereux RB et al. Mitral valve prolapse in the general population. Epidemiologic features: the Framingham Study. Am Heart J 1983;106:571–576.PubMedGoogle Scholar
  2. 2.
    Freed LA, Levy D, Levine RA et al. Prevalence and clinical outcome of mitral-valve prolapse. N Engl J Med 1999;341:1–7.PubMedGoogle Scholar
  3. 3.
    The changing spectrum of valvular heart disease pathology. In: Braunwald E (ed) Harrison’s advances in cardiology. New York: McGraw-Hill, 2002; pp 317–323.Google Scholar
  4. 4.
    Hayek E, Gring CN, Griffin BP. Mitral valve prolapse. Lancet 2005;365:507–518.PubMedGoogle Scholar
  5. 5.
    Enriquez-Sarano M, Akins CW, Vahanian A. Mitral regurgitation. Lancet 2009; 373:1382–1394.PubMedGoogle Scholar
  6. 6.
    Barlow JB, Pocock WA. Mitral valve prolapse, the specific billowing mitral leaflet syndrome, or an insignificant non-ejection systolic click. Am Heart J 1979;97:277–285.PubMedGoogle Scholar
  7. 7.
    Abrams J. Mitral valve prolapse: a plea for unanimity. Am Heart J 1976;92:413–415.PubMedGoogle Scholar
  8. 8.
    Ling LH, Enriquez-Sarano M, Seward JB et al. Clinical outcome of mitral regurgitation due to flail leaflet. N Engl J Med 1996;335:1417–1423.PubMedGoogle Scholar
  9. 9.
    Rosen SE, Borer JS, Hochreiter C et al. Natural history of the asymptomatic/minimally symptomatic patient with severe mitral regurgitation secondary to mitral valve prolapse and normal right and left ventricular performance. Am J Cardiol 1994;74:374–380.PubMedGoogle Scholar
  10. 10.
    Nkomo VT, Gardin JM, Skelton TN et al. Burden of valvular heart diseases: a populationbased study. Lancet 2006;368:1005–1011.PubMedGoogle Scholar
  11. 11.
    Iung B, Baron G, Butchart EG et al. A prospective survey of patients with valvular heart disease in Europe: the Euro Heart Survey on Valvular Heart Disease. Eur Heart J 2003;24:1231–1243.PubMedGoogle Scholar
  12. 12.
    Mirabel M, Iung B, Baron G et al. What are the characteristics of patients with severe, symptomatic, mitral regurgitation who are denied surgery? Eur Heart J 2007;28:1358–1365.PubMedGoogle Scholar
  13. 13.
    Bach DS, Awais M, Gurm HS, Kohnstamm S. Failure of guideline adherence for intervention in patients with severe mitral regurgitation. J Am Coll Cardiol 2009;54:860–865.PubMedGoogle Scholar
  14. 14.
    David TE, Ivanov J, Armstrong S, Rakowski H. Late outcomes of mitral valve repair for floppy valves: implications for asymptomatic patients. J Thorac Cardiovasc Surg 2003;125:1143–1152.PubMedGoogle Scholar
  15. 15.
    Adams DH, Anyanwu AC, Rahmanian PB, Filsoufi F. Current concepts in mitral valve repair for degenerative disease. Heart Fail Rev 2006;11:241–257.PubMedGoogle Scholar
  16. 16.
    Enriquez-Sarano M, Tajik AJ. Natural history of mitral regurgitation due to flail leaflets. Eur Heart J 1997;18:705–707.PubMedGoogle Scholar
  17. 17.
    St John Sutton M, Weyman AE. Mitral valve prolapse prevalence and complications: an ongoing dialogue. Circulation 2002;106:1305–1307.PubMedGoogle Scholar
  18. 18.
    Enriquez-Sarano M, Avierinos JF, Messika-Zeitoun D et al. Quantitative determinants of the outcome of asymptomatic mitral regurgitation. N Engl J Med 2005;352:875–883.PubMedGoogle Scholar
  19. 19.
    Chenot F, Montant P, Vancraeynest D et al. Long-term clinical outcome of mitral valve repair in asymptomatic severe mitral regurgitation. Eur J Cardiothorac Surg 2009;36:539–545.PubMedGoogle Scholar
  20. 20.
    Montant P, Chenot F, Robert A et al. Long-term survival in asymptomatic patients with severe degenerative mitral regurgitation: a propensity score-based comparison between an early surgical strategy and a conservative treatment approach. J Thorac Cardiovasc Surg 2009;138:1339–1348.PubMedGoogle Scholar
  21. 21.
    Zoghbi WA, Enriquez-Sarano M, Foster E et al. American Society of Echocardiography. Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and Doppler echocardiography. J Am Soc Echocardiogr 2003;16:777–802.PubMedGoogle Scholar
  22. 22.
    Enriquez-Sarano M, Schaff HV, Orszulak TA et al. Valve repair improves the outcome of surgery for mitral regurgitation. A multivariate analysis. Circulation 1995;91:1022–1028.PubMedGoogle Scholar
  23. 23.
    David TE. Outcomes of mitral valve repair for mitral regurgitation due to degenerative disease. Semin Thorac Cardiovasc Surg 2007;19:116–120.PubMedGoogle Scholar
  24. 24.
    Savage EB, Ferguson TB Jr, DiSesa VJ. Use of mitral valve repair: analysis of contemporary United States experience reported to the Society of Thoracic Surgeons National Cardiac Database. Ann Thorac Surg 2003;75:820–825.PubMedGoogle Scholar
  25. 25.
    Braunberger E, Deloche A, Berrebi A et al. Very long-term results (more than 20 years) of valve repair with Carpentier’s techniques in nonrheumatic mitral valve insufficiency. Circulation 2001;104(12 Suppl 1):I8–11.PubMedGoogle Scholar
  26. 26.
    David TE, Ivanov J, Armstrong S et al. A comparison of outcomes of mitral valve repair for degenerative disease with posterior, anterior, and bileaflet prolapse. J Thorac Cardiovasc Surg 2005;130:1242–1249.PubMedGoogle Scholar
  27. 27.
    Frater RW. Chordal sparing mitral valve replacement. J Heart Valve Dis 1999;8:42–43.PubMedGoogle Scholar
  28. 28.
    Yun KL, Sintek CF, Miller DC et al. Randomized trial comparing partial versus complete chordal-sparing mitral valve replacement: effects on left ventricular volume and function. J Thorac Cardiovasc Surg 2002;123:707–714.PubMedGoogle Scholar
  29. 29.
    Moss RR, Humphries KH, Gao M et al. Outcome of mitral valve repair or replacement: a comparison by propensity score analysis. Circulation 2003;108(Suppl 1);II90–97.PubMedGoogle Scholar
  30. 30.
    Rosenhek R, Rader F, Klaar U et al. Outcome of watchful waiting in asymptomatic severe mitral regurgitation. Circulation 2006;113:2238–2244.PubMedGoogle Scholar
  31. 31.
    American College of Cardiology/American Heart Association Task Force on Practice Guidelines; Society of Cardiovascular Anesthesiologists; Society for Cardiovascular Angiography and Interventions; Society of Thoracic Surgeons, Bonow RO, Carabello BA, Kanu C et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. Circulation 2006;114:e84–231.Google Scholar
  32. 32.
    Vahanian A, Baumgartner H, Bax J et al, Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology; ESC Committee for Practice Guidelines. Guidelines on the management of valvular heart disease: The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology. Eur Heart J 2007;28:230–268.PubMedGoogle Scholar
  33. 33.
    Carpentier A, Deloche A, Dauptain J et al. A new reconstructive operation for correction of mitral and tricuspid insufficiency. J Thorac Cardiovasc Surg 1971;61:1–13.PubMedGoogle Scholar
  34. 34.
    Carpentier A. Cardiac valve surgery — the “French correction”. J Thorac Cardiovasc Surg 1983;86:323–337.PubMedGoogle Scholar
  35. 35.
    Jebara VA, Mihaileanu S, Acar C et al. Left ventricular outflow tract obstruction after mitral valve repair. Results of the sliding leaflet technique. Circulation 1993;88:II30–34.PubMedGoogle Scholar
  36. 36.
    Saunders PC, Grossi EA, Schwartz CF et al. Anterior leaflet resection of the mitral valve. Semin Thorac Cardiovasc Surg 2004;16:188–193.PubMedGoogle Scholar
  37. 37.
    Galloway AC, Grossi EA, Bizekis CS et al. Evolving techniques for mitral valve reconstruction. Ann Surg 2002;236:288–293.PubMedGoogle Scholar
  38. 38.
    Grossi A, La Pietra A, Galloway AC, Colvin SB. History of mitral valve anterior leaflet repair with triangular resection. Ann Thorac Surg 2001;72:1794–1795.PubMedGoogle Scholar
  39. 39.
    Grossi EA, Galloway AC, LeBoutillier M 3rd et al. Anterior leaflet procedures during mitral valve repair do not adversely influence long-term outcome. J Am Coll Cardiol 1995;25:134–136.PubMedGoogle Scholar
  40. 40.
    Grossi EA, Steinberg BM, LeBoutillier M 3rd et al. Decreasing incidence of systolic anterior motion after mitral valve reconstruction. Circulation 1994;90:II195–197.PubMedGoogle Scholar
  41. 41.
    Smedira NG, Selman R, Cosgrove DM et al. Repair of anterior leaflet prolapse: chordal transfer is superior to chordal shortening. J Thorac Cardiovasc Surg 1996;112:287–291.PubMedGoogle Scholar
  42. 42.
    Salati M, Moriggia S, Scrofani R, Santoli C. Chordal transposition for anterior mitral prolapse: early and long-term results. Eur J Cardiothorac Surg 1997;11:268–273.PubMedGoogle Scholar
  43. 43.
    Salati M, Scrofani R, Fundaró P et al. Correction of anterior mitral prolapse. Results of chordal transposition. J Thorac Cardiovasc Surg 1992;104:1268–1273.PubMedGoogle Scholar
  44. 44.
    Gillinov AM, Cosgrove DM. Chordal transfer for repair of anterior leaflet prolapse. Semin Thorac Cardiovasc Surg 2004;16:169–173.PubMedGoogle Scholar
  45. 45.
    David TE. Artificial chordae. Semin Thorac Cardiovasc Surg 2004;16:161–168.PubMedGoogle Scholar
  46. 46.
    David TE, Omran A, Armstrong S et al. Long-term results of mitral valve repair for myxomatous disease with and without chordal replacement with expanded polytetrafluoroethylene sutures. J Thorac Cardiovasc Surg 1998;115:1279–1285.PubMedGoogle Scholar
  47. 47.
    Phillips MR, Daly RC, Schaff HV et al. Repair of anterior leaflet mitral valve prolapse: chordal replacement versus chordal shortening. Ann Thorac Surg 2000;69:25–29.PubMedGoogle Scholar
  48. 48.
    von Oppell UO, Mohr FW. Chordal replacement for both minimally invasive and conventional mitral valve surgery using premeasured Gore-Tex loops. Ann Thorac Surg 2000;70:2166–2168.Google Scholar
  49. 49.
    Kuntze T, Borger MA, Falk V et al. Early and mid-term results of mitral valve repair using premeasured Gore-Tex loops (“loop technique”). Eur J Cardiothorac Surg 2008;33:566–572.PubMedGoogle Scholar
  50. 50.
    Perier P, Hohenberger W, Lakew F et al. Toward a new paradigm for the reconstruction of posterior leaflet prolapse: midterm results of the “respect rather than resect” approach. Ann Thorac Surg 2008;86:718–725.PubMedGoogle Scholar
  51. 51.
    Maisano F, Torracca L, Oppizzi M et al. The edge-to-edge technique: a simplified method to correct mitral insufficiency. Eur J Cardiothorac Surg 1998;13:240–245; discussion 245-246.PubMedGoogle Scholar
  52. 52.
    Maisano F, Schreuder JJ, Oppizzi M et al. The double-orifice technique as a standardized approach to treat mitral regurgitation due to severe myxomatous disease: surgical technique. Eur J Cardiothorac Surg 2000;17:201–205.PubMedGoogle Scholar
  53. 53.
    Alfieri O, Maisano F, De Bonis M et al. The double-orifice technique in mitral valve repair: a simple solution for complex problems. J Thorac Cardiovasc Surg 2001;122:674–681.PubMedGoogle Scholar
  54. 54.
    Alfieri O, De Bonis M, Lapenna E et al. “Edge-to-edge” repair for anterior mitral leaflet prolapse. Semin Thorac Cardiovasc Surg 2004;16:182–187.PubMedGoogle Scholar
  55. 55.
    Alfieri O, Maisano F. An effective technique to correct anterior mitral leaflet prolapse. J Card Surg 1999;14:468–470.PubMedGoogle Scholar
  56. 56.
    Dreyfus GD, Bahrami T, Alayle N et al. Repair of anterior leaflet prolapse by papillary muscle repositioning: a new surgical option. Ann Thorac Surg 2001;71:1464–1470.PubMedGoogle Scholar
  57. 57.
    Dreyfus G, Al Aylé N, Dubois C, Lentdecker P. Long term results of mitral valve repair: posterior papillary muscle repositioning versus chordal shortening. Eur J Cardiothorac Surg 1999;16:81–87.PubMedGoogle Scholar
  58. 58.
    Adams DH, Anyanwu AC, Rahmanian PB, Filsoufi F. Current concepts in mitral valve repair for degenerative disease. Heart Fail Rev 2006;11:241–257.PubMedGoogle Scholar
  59. 59.
    Chen FY, Cohn LH. Mitral valve repair. In: Cohn LH (ed) Cardiac surgery in the adult. New York: McGraw-Hill, 2008; pp 1013–1030.Google Scholar
  60. 60.
    Fedak PW, McCarthy PM, Bonow RO. Evolving concepts and technologies in mitral valve repair. Circulation 2008;117:963–974.PubMedGoogle Scholar
  61. 61.
    De Bonis M, Lorusso R, Lapenna E et al. Similar long-term results of mitral valve repair for anterior compared with posterior leaflet prolapse. J Thorac Cardiovasc Surg 2006;131:364–370.PubMedGoogle Scholar
  62. 62.
    Gillinov AM, Cosgrove DM, Blackstone EH et al. Durability of mitral valve repair for degenerative disease. J Thorac Cardiovasc Surg 1998;116:734–743.PubMedGoogle Scholar
  63. 63.
    Mohty D, Orszulak TA, Schaff HV et al. Very long-term survival and durability of mitral valve repair for mitral valve prolapse. Circulation 2001;104:I1–I7.PubMedGoogle Scholar
  64. 64.
    Deloche A, Jebara VA, Relland JY et al. Valve repair with Carpentier techniques. The second decade. J Thorac Cardiovasc Surg 1990;99:990–1001.Google Scholar
  65. 65.
    Perier P, Stumpf J, Götz C et al. Valve repair for mitral regurgitation caused by isolated prolapse of the posterior leaflet. Ann Thorac Surg 1997;64:445–450.PubMedGoogle Scholar
  66. 66.
    Tribouilloy CM, Enriquez-Sarano M, Schaff HV et al. Impact of preoperative symptoms on survival after surgical correction of organic mitral regurgitation: rationale for optimizing surgical indications. Circulation 1999;99:400–405.PubMedGoogle Scholar
  67. 67.
    Enriquez-Sarano M, Tajik AJ, Schaff HV et al. Echocardiographic prediction of survival after surgical correction of organic mitral regurgitation. Circulation 1994;90:830–837.PubMedGoogle Scholar
  68. 68.
    O’Brien SM, Shahian DM, Filardo G et al, Society of Thoracic Surgeons Quality Measurement Task Force. The Society of Thoracic Surgeons 2008 cardiac surgery risk models: part 2 — isolated valve surgery. Ann Thorac Surg 2009;88:S23–42.PubMedGoogle Scholar
  69. 69.
    Adams DH, Anyanwu AC, Rahmanian PB et al. Large annuloplasty rings facilitate mitral valve repair in Barlow’s disease. Ann Thorac Surg 2006;82:2096–2100.PubMedGoogle Scholar
  70. 70.
    Flameng W, Meuris B, Herijgers P, Herregods MC. Durability of mitral valve repair in Barlow disease versus fibroelastic deficiency. J Thorac Cardiovasc Surg 2008;135:274–282.PubMedGoogle Scholar
  71. 71.
    Flameng W, Herijgers P, Bogaerts K. Recurrence of mitral valve regurgitation after mitral valve repair in degenerative valve disease. Circulation 2003;107:1609–1613.PubMedGoogle Scholar
  72. 72.
    Grande Allen KJ, Borowski AG, Troughton RW et al. Apparently normal mitral valves in patients with heart failure demonstrate biochemical and structural derangements. An extracellular matrix and echocardiographic study. J Am Coll Cardiol 2005;45:54–61.PubMedGoogle Scholar
  73. 73.
    Grande Allen KJ, Barber JA, Klatka KM et al. Mitral valve stiffening in end-stage heart failure: Evidence of an organic contribution to functional mitral regurgitation. J Thorac Cardiovasc Surg 2005;130:783–790.PubMedGoogle Scholar
  74. 74.
    Chaput M, Handschumacher MD, Tournoux F et al. Mitral leaflet adaptation to ventricular remodeling: occurrence and adequacy in patients with functional mitral regurgitation. Circulation 2008;118;845–852.PubMedGoogle Scholar
  75. 75.
    Dal Bianco JP, Aikawa E, Bischoff J et al. Active adaptation of the tethered mitral valve. Insights into a compensatory mechanism for functional mitral regurgitation. Circulation 2009;120:334–342Google Scholar
  76. 76.
    Carabello BA, Nakano K, Corin W et al. Left ventricular function in experimental volume overload hypertrophy. Am J Physiol Heart Circ Physiol 1989;256:H974–981.Google Scholar
  77. 77.
    Urabe Y, Mann DL, Kent RL et al. Cellular and ventricular contractile dysfunction in experimental canine mitral regurgitation. Circ Res 1992;70:131–147.PubMedGoogle Scholar
  78. 78.
    Ishihara K, Zile MR, Kanazawa S et al. Left ventricular mechanics and myocyte function after correction of experimental chronic mitral regurgitation by combined mitral valve replacement and preservation of the native mitral valve apparatus. Circulation 1992;86:16–25.Google Scholar
  79. 79.
    Spinale FG, Ishihra K, Zile MR et al. Structural basis for changes in left ventricular function and geometry because of chronic mitral regurgitation and after correction of volume overload. J Thorac Cardiovasc Surg 1993;106:1147–1157.PubMedGoogle Scholar
  80. 80.
    Corin WJ, Monrad ES, Murakami T et al. The relationship of afterload to ejection performance in chronic mitral regurgitation. Circulation 1987;76:59–67.PubMedGoogle Scholar
  81. 81.
    Zile MR, Gaasch WH, Levine HT. Left ventricular stress-dimension shortening relations before and after correction of chronic aortic and mitral regurgitation. Am J Cardiol 1985;56:99.PubMedGoogle Scholar
  82. 82.
    Dell’Italia LJ, Meng QC, Balcells E et al. Increased ACE and chymase-like activity in cardiac tissue of dogs with chronic mitral regurgitation. Am J Physiol Heart Circ Physiol 1995;269:02065–2073.Google Scholar
  83. 83.
    Kapadia SR, Yakoob K, Nader S et al. Elevated circulating levels of serum tumor necrosis factor-alpha in patients with hemodynamically significant pressure and volume overload. J Am Coll Cardiol 2000;36:208–212.PubMedGoogle Scholar
  84. 84.
    Talwar S, Squire IB, Davies JE, Ng LL. The effect of valvular regurgitation on plasma cardiotrophin-1 in patients with normal left ventricular systolic function. Eur J Heart Fail 2000;2:387–391.PubMedGoogle Scholar
  85. 85.
    Otsuji Y, Handschumacher MD, Liel-Cohen N et al. Mechanism of ischemic mitral regurgitation with segmental left ventricular dysfunction: three-dimensional echocardiographic studies in models of acute and chronic progressive regurgitation. J Am Coll Cardiol 2001;37:641–648.PubMedGoogle Scholar
  86. 86.
    Liel-Cohen N, Guerrero JL, Otsuji Y et al. Design of a new surgical approach for ventricular remodeling to relieve ischemic mitral regurgitation. Circulation 2000;101:2756–2763PubMedGoogle Scholar
  87. 87.
    Hung J, Papakostas L, Tahta SA et al. Mechanism of recurrent ischemic mitral regurgitation post-annuloplasty: continued LV remodeling as a moving target. Circulation 2004;110:85–90.Google Scholar
  88. 88.
    Beeri R, Yosefy C, Guerrero JL et al. Early repair of moderate ischemic mitral regurgitation reverses left ventricular remodeling. A functional and molecular study. Circulation 2007;116(Suppl I):I288–293.PubMedGoogle Scholar
  89. 89.
    St. John SM, Pfeffer MA, Plappert T et al. Quantitative twodimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril. Circulation 1994;89:68–75.Google Scholar
  90. 90.
    Caimmi PP, Diterlizzi M, Grossini E et al. Impact of prosthetic mitral rings on aortomitral apparatus function: a cardiac magnetic resonance imaging study. Ann Thorac Surg 2009;88:740–744.PubMedGoogle Scholar
  91. 91.
    Enriquez-Sarano M, Loulmet DF, Burkhoff D. The conundrum of functional mitral regurgitation in chronic heart failure. J Am Coll Cardiol 2008;51;487–489.PubMedGoogle Scholar
  92. 92.
    Vahanian A, Baumgartner H, Bax J et al. Guidelines on the management of valvular heart disease. The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology. Eur Heart J 2007;28:230–268.PubMedGoogle Scholar
  93. 93.
    Bonow RO, Carabello BA, Chatterjee K et al, American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2008 focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to revise the 1998 guidelines for the management of patients with valvular heart disease). Endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol 2008;52:e1–142.PubMedGoogle Scholar
  94. 94.
    Otto CM. Evaluation and management of chronic mitral regurgitation. N Engl J Med 2001;345:740–746.PubMedGoogle Scholar
  95. 95.
    Koelling TM, Aaronson KD, Cody RJ et al. Prognostic significance of mitral regurgitation and tricuspid regurgitation in patients with left ventricular systolic dysfunction. Am Heart J 2002;144:524–529.PubMedGoogle Scholar
  96. 96.
    Trichon BH, Felker GM, Shaw LK et al. Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure. Am J Cardiol 2003;91:538–543.PubMedGoogle Scholar
  97. 97.
    Robbins JD, Maniar PB, Cotts W et al. Prevalence and severity of mitral regurgitation in chronic systolic heart failure. Am J Cardiol 2003;91:360–362.PubMedGoogle Scholar
  98. 98.
    Bach DS, Awais M, Gurm HS, Kohnstamm S. Failure of guideline adherence for intervention in patients with severe mitral regurgitation. J Am Coll Cardiol 2009;54:860–865.PubMedGoogle Scholar
  99. 99.
    Bolling SF, Pagani FD, Deeb GM, Bach DS. Intermediate-term outcome of mitral reconstruction in cardiomyopathy. J Thorac Cardiovasc Surg 1998;115:381–386.PubMedGoogle Scholar
  100. 100.
    Wu AH, Aaronson KD, Bolling SF et al. Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction. J Am Coll Cardiol 2005;45:381–387.PubMedGoogle Scholar
  101. 101.
    Acker MA, Bolling S, Shemin R et al. Mitral valve surgery in heart failure: insights from the Acorn Clinical Trial. J Thorac Cardiovasc Surg 2006;132:568–577.PubMedGoogle Scholar
  102. 102.
    Calafiore AM, Gallina S, Di Mauro M et al. Mitral valve procedure in dilated cardiomyopathy: repair or replacement? Ann Thorac Surg 2001;71:1146–1152.PubMedGoogle Scholar
  103. 103.
    Grigioni F, Enriquez-Sarano M, Zehr KJ et al. Ischemic mitral regurgitation. Long term outcome and prognostic implication with quantitative Doppler assessment. Circulation 2001;103:1759–1764.PubMedGoogle Scholar
  104. 104.
    Grigioni F, Detaint D, Avierinos J-F et al. Contribution of ischemic mitral regurgitation to congestive heart failure after myocardial infarction. J Am Coll Cardiol 2005;45:260–267.PubMedGoogle Scholar
  105. 105.
    Aronson D, Goldsher N, Zukerman R et al. Ischemic mitral regurgitation and risk of heart failure after myocardial infarction. Arch Intern Med 2006;166:2362–2368.PubMedGoogle Scholar
  106. 106.
    Schroder JN, Williams ML, Hata JA et al. Impact of mitral valve regurgitation evaluated by intraoperative transesophageal echocardiography on long-term outcomes after coronary artery bypass grafting. Circulation 2005;112(Suppl I):I293–298.PubMedGoogle Scholar
  107. 107.
    Amigoni M, Meris A, Thune JJ et al. Mitral regurgitation in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: prognostic significance and relation to ventricular size and function. Eur Heart J 2007;28; 326–333.PubMedGoogle Scholar
  108. 108.
    Di Mauro M, Di Giammarco G, Vitolla G et al. Impact of no-or-moderate mitral regurgitation on late results after isolated coronary artery bypass grafting in patients with ischemic cardiomyopathy. Ann Thorac Surg 2006;81:2128–2134.PubMedGoogle Scholar
  109. 109.
    Calafiore AM, Mazzei V, Iacò AL et al. Impact of ischemic regurgitation on long-term outcome of patients with ejection fraction above 0.30 undergoing first isolated myocardial revascularization. Ann Thorac Surg 2008;86:458–465.PubMedGoogle Scholar
  110. 110.
    Fattouch K, Guccione F, Sampognaro R et al. POINT: efficacy of adding mitral valve restrictive annuloplasty to coronary artery bypass grafting in patients with moderate ischemic mitral valve regurgitation: a randomized trial. J Thorac Cardiovasc Surg 2009;138:278–285.PubMedGoogle Scholar
  111. 111.
    Kinkaid EH, Riley RD, Hines MH et al. Anterior leaflet augmentation for ischemic mitral regurgitation. Ann Thorac Surg 2004;78:564–568.Google Scholar
  112. 112.
    Romano MA, Patel HJ, Pagani FD et al. Anterior leaflet repair with patch augmentation for mitral regurgitation. Ann Thorac Surg 2005;79:1500–1504.PubMedGoogle Scholar
  113. 113.
    Aubert S, Flecher E, Rubin S et al. Anterior mitral leaflet augmentation with autologous pericardium. Ann Thorac Surg 2007;83:1560–1561.PubMedGoogle Scholar
  114. 114.
    De Varennes B, Chaturvedi R, Sidhu S et al. Initial results of posterior leaflet extension for severe type IIIb ischemic mitral regurgitation. Circulation 2009;119:2837–2843.PubMedGoogle Scholar
  115. 115.
    Messas E, Pouzet B, Touchot B et al. Efficacy of chordal cutting to relieve chronic persistent ischemic mitral regurgitation. Circulation 2003;108(Suppl 1):II111–115.PubMedGoogle Scholar
  116. 116.
    Borger MA, Murphy PM, Alam A et al. Initial results of the chordal-cutting operation for ischemic mitral regurgitation. J Thorac Cardiovasc Surg 2007;133:1483–1492.PubMedGoogle Scholar
  117. 117.
    Nielsen SL, Timek TA, Green GR et al. Influence of anterior mitral leaflet second-order chordae tendineae on left ventricular systolic function. Circulation 2003;108:486–491.PubMedGoogle Scholar
  118. 118.
    Aazami MH, Salehi M, Satarzadeh R. Whatever the approach, cutting strut chordae would not smell as sweet (letter). J Thorac Cardiovasc Surg 2005;130:1480.PubMedGoogle Scholar
  119. 119.
    Braun J, van der Veire NR, Klautz RJM et al. Restrictive mitral annuloplasty cures ischemic mitral regurgitation and heart failure. Ann Thorac Surg 2008;85:430–437.PubMedGoogle Scholar
  120. 120.
    Srichai MB, Grimm RA, Stillman AE et al. Ischemic mitral regurgitation: impact of left ventricle and mitral valve in patients with left ventricular dysfunction. Ann Thorac Surg 2005;80:170–178.PubMedGoogle Scholar
  121. 121.
    Hvaas U, Tapia M, Baron F et al. Papillary muscle sling: a new functional approach to mitral valve repair in patients with ischemic left ventricular dysfunction and functional mitral regurgitation. Ann Thorac Surg 2003;75:809–811.Google Scholar
  122. 122.
    Fumimoto K, Fukui T, Shimokawa T, Takanashi S. Papillary muscle realignment and mitral annuloplasty in patients with severe ischemic mitral regurgitation and dilated heart. Interact Cardiovasc Thorac Surg 2008;7:368–371.PubMedGoogle Scholar
  123. 123.
    Kron IL, Green GR, Cope JT. Surgical relocation of the posterior papillary muscle in chronic ischemic mitral regurgitation. Ann Thorac Surg 2002;74:600–601.PubMedGoogle Scholar
  124. 124.
    Ueno T, Sakata R, Iguro Y et al. New surgical approach to reduce tethering in ischemic mitral regurgitation by relocation of separate heads of the posterior papillary muscle. Ann Thorac Surg 2006;81:2324–2325.PubMedGoogle Scholar
  125. 125.
    Rama A, Praschker L, Barreda E, Gandjbackhch I. Papillary muscle approximation for functional ischemic mitral regurgitation. Ann Thorac Surg 2007:84:2130–2131.PubMedGoogle Scholar
  126. 126.
    Langer F, Schäfers H-J. RING plus STRING: papillary muscle repositioning as an adjunctive repair technique for ischemic mitral regurgitation. J Thorac Cardiovasc Surg 2007;133:247–249.PubMedGoogle Scholar
  127. 127.
    Crabtree TD, Bailey MS, Moon MR et al. Recurrent mitral regurgitation and risk factors for early and late mortality after mitral valve repair for functional ischemic mitral regurgitation. Ann Thorac Surg 2008;85:1537–1543.PubMedGoogle Scholar
  128. 128.
    Zhu F, Otsuji Y, Yotsumoto G et al. Mechanism of persistent ischemic mitral regurgitation after annuloplasty: importance of augmented posterior mitral leaflet tethering. Circulation 2005;112:I396–1401.PubMedGoogle Scholar
  129. 129.
    Yiu SF, Enriquez-Sarano M, Tribouilloy C et al. Determinants of the degree of functional mitral regurgitation in patients with systolic left ventricular dysfunction: a quantitative clinical study. Circulation 2000;102:1400–1406.PubMedGoogle Scholar
  130. 130.
    De Bonis M, Lapenna E, Verzini A et al. Recurrence of mitral regurgitation parallels the absence of left ventricular reverse remodeling after mitral repair in advanced dilated cardiomyopathy. Ann Thorac Surg 2008;85:932–939.PubMedGoogle Scholar
  131. 131.
    Pui-Wai Lee A, Acker M, Kubo SH et al. Mechanisms of recurrent functional mitral regurgitation after mitral valve repair in non schemic dilated cardiomyopathy. Importance of distal anterior leaflet tethering. Circulation 2009;119:2606–2614.Google Scholar
  132. 132.
    Szalay ZA, Civelek A, Hohe S et al. Mitral annuloplasty in patients with ischemic versus dilated cardiomyopathy. Eur J Cardiothorac Surg 2003:23:567–572.PubMedGoogle Scholar
  133. 133.
    Glower DD, Tuttle RH, Shaw LK et al. Patients survival characteristics after routine mitral valve repair for ischemic mitral regurgitation. J Thorac Cardiovasc Surg 2005;129:860–868.PubMedGoogle Scholar
  134. 134.
    De Bonis M, La Penna E, La Canna G et al. Mitral valve repair for functional mitral regurgitation in end-stage dilated cardiomyopathy. Role of the edge-to-edge technique. Circulation 2005;112(Suppl I):I402–408.PubMedGoogle Scholar
  135. 135.
    Mihaljevic T, Lam B-K, Rajeswaran J et al. Impact of mitral valve annuloplasty combined with revascularization in patients with functional ischemic mitral regurgitation. J Am Coll Cardiol 2007;49:2191–2201.PubMedGoogle Scholar
  136. 136.
    Gelsomino S, Lorusso R, De Cicco G et al. Five-year echocardiographic results of combined undersized mitral ring annuloplasty and coronary artery bypass grafting for chronic ischemic mitral regurgitation. Eur Heart J 2008;29:231–240.PubMedGoogle Scholar
  137. 137.
    Al-Radi OO, Austin PC, Tu JV et al. Mitral repair versus replacement for ischemic mitral rgurgitation. Ann Thorac Surg 2005;79:1260–1267.PubMedGoogle Scholar
  138. 138.
    Magne J, Senechal M, Mathieu P et al. Short-and long-term survival of mitral valve repair versus mitral valve replacement in patients with functional mitral regurgitation. Circulation 2008;118:S698.Google Scholar
  139. 139.
    Magne J, Pibarot P, Dagenais F et al. Preoperative posterior leaflet angle accurately predicts outcome after restrictive mitral valve annuloplasty for ischemic mitral regurgitation. Circulation 2007;115:782–791.PubMedGoogle Scholar
  140. 140.
    Gelsomino S, Lorusso R, Caciolli S et al. Insights on left ventricular mechanisms of recurrent ischemic mitral regurgitation after restrictive annuloplasty and coronary artery bypass grafting. J Thorac Cardiovasc Surg 2008;136:507–518.PubMedGoogle Scholar
  141. 141.
    Roshanali F, Mandegar MH, Yousefnia MA et al. A prospective study of predicting factors in ischemic mitral regurgitation recurrence after ring annuloplasty. Ann Thorac Surg 2007;84:745–749.PubMedGoogle Scholar
  142. 142.
    Bolman III RM. Have we found the surgical solution for ischemic mitral regurgitation? Circulation 2009;119:2755–2757.PubMedGoogle Scholar
  143. 143.
    Magne J, Sénéchal M, Mathieu P et al. Restrictive annuloplasty for ischemic mitral regurgitation may induce functional mitral stenosis. J Am Coll Cardiol 2008;51:1692–1701.PubMedGoogle Scholar
  144. 144.
    Williams ML, Daneshmand MA, Jollis JG et al. Mitral gradients and frequency of recurrence of mitral regurgitation after ring annuloplasty for ischemic mitral regurgitation. Ann Thorac Surg 2009;88:1197–1201.PubMedGoogle Scholar
  145. 145.
    Bonow RO, Carabello BA, Chatterjee K et al. 2008 Focused Update incorporated into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease) Endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol 2008;52;e1–e142.PubMedGoogle Scholar
  146. 146.
    Otto CM. Valvular aortic stenosis. Disease severity and timing of intervention. J Am Coll Cardiol 2006;47:2141–2151.PubMedGoogle Scholar
  147. 147.
    Pai RG, Kapoor N, Bansal RC, Varadarajan P. Malignant natural history of asymptomatic severe aortic stenosis: benefit of aortic valve replacement. Ann Thorac Surg 2006;82:2116–2122.PubMedGoogle Scholar
  148. 148.
    Jamieson WRE, Ye J, Higgins J et al. Effects of prosthesis-patient mismatch on long-term survival with aortic valve replacement: assessment to 15 years. Ann Thorac Surg 2010;89:51–59.PubMedGoogle Scholar
  149. 149.
    Iung B, Cachier A, Baron G et al. Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery? Eur Heart J 2005;26:2714–2720.PubMedGoogle Scholar
  150. 150.
    Bach DS, Cimino N, Deeb GM. Unoperated patients with severe aortic stenosis. J Am Coll Cardiol 2007;50:2018–2019.PubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia 2010

Authors and Affiliations

  • Corrado Tamburino
    • 1
  • Gian Paolo Ussia
    • 2
  1. 1.Ferrarotto HospitalUniversity of Catania, ETNA FoundationCataniaItaly
  2. 2.Cardiology DivisionFerrarotto HospitalCataniaItaly

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