Neonatology pp 540-542 | Cite as

Lung Diseases: Problems of Steroid Treatment of Fetus and Newborn

  • Henry L. Halliday


Corticosteroids given in the perinatal period have a multitude of biologic effects on the developing lung [1]. These include reduced alveolarization, increased production of surfactant lipids and proteins, increased absorption of lung fluid and increased antioxidant activity. Clearly some of these will be beneficial to the immature fetus or neonate whilst others will be detrimental. Thus administration of corticosteroids in the perinatal period must be based upon clinical judgment of the balance of benefits and risks.


Cerebral Palsy Respiratory Distress Syndrome Preterm Birth Chronic Lung Disease Periventricular Leukomalacia 
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Copyright information

© Springer-Verlag Italia 2012

Authors and Affiliations

  • Henry L. Halliday
    • 1
    • 2
  1. 1.Regional Neonatal UnitRoyal Maternity HospitalBelfastNorthern Ireland
  2. 2.Department of Child HealthQueen’s University BelfastBelfastNorthern Ireland

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