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Neonatology pp 529-536 | Cite as

Nitric Oxide Therapy in Neonatology

  • John P. Kinsella

Abstract

After multiple approaches to the treatment of PPHN (see  Chapter 67) since its first recognition as a disease marked by severe pulmonary hypertension, the discovery of the elusive “selective pulmonary vasodilator” markedly changed our understanding and clinical management of this syndrome. The most striking change in the management of PPHN in the last decade evolved from an improved understanding of the role of endogenous NO production and exogenous NO delivery on pulmonary vasoregulation.

Keywords

Nitric Oxide Pulmonary Hypertension Pulmonary Vascular Resistance Oxygenation Index Severe Pulmonary Hypertension 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2012

Authors and Affiliations

  • John P. Kinsella
    • 1
    • 2
  1. 1.Department of Pediatrics, Section of NeonatologyUniversity of Colorado School of MedicineDenverUSA
  2. 2.Children’s Hospital ColoradoDenverUSA

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