Neonatology pp 387-404 | Cite as

Lung Development and Pulmonary Malformations

  • Corrado Moretti
  • Paola Papoff


In the early weeks of gestation the human lung originates as a ventral endodermal pouch from the primitive foregut; it thereafter continues to grow through to adulthood until it reaches an exchange surface area of around 70–100 m2; the air-blood barrier is some 0.2 microns thick, 1/50 of the thickness of a sheet of tissue paper.


Fetal Lung Congenital Diaphragmatic Hernia Noonan Syndrome Pulmonary Hypoplasia Bronchogenic Cyst 
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© Springer-Verlag Italia 2012

Authors and Affiliations

  • Corrado Moretti
    • 1
  • Paola Papoff
  1. 1.Pediatric Emergency Medicine Unit Department of Pediatrics‘Sapienza’ University of RomeRomeItaly

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