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Neonatology pp 1079-1086 | Cite as

Inflammation and Perinatal Brain Injury

  • Henrik Hagberg
  • Carina Mallard
  • Karin Sävman

Abstract

Inflammation is a systemic and local immune reaction to injury secondary to microbial invasion or other damaging events like trauma and hypoxia-ischemia (Fig. 128.1). This response aids in identifying extrinsic pathogens and kills microbes (and affected cells) if the injury is caused by infection [1]. Irrespective of the primary triggering event, inflammation often causes brain damage during its acute stage (collateral damage) followed by a secondary phase that in most cases promotes tissue repair and regeneration [2].

Keywords

Cerebral Palsy White Matter Injury Spastic Cerebral Palsy Microbial Invasion Neonatal Encephalopathy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2012

Authors and Affiliations

  • Henrik Hagberg
    • 1
  • Carina Mallard
  • Karin Sävman
  1. 1.Institute of Reproductive and Developmental BiologyImperial CollegeLondonUK

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