Abstract
The detection and identification of viral infections in newborns has been greatly improved by the recent development of rapid and highly sensitive diagnostic methods, particularly polymerase chain reaction (PCR) techniques. Data from a retrospective analysis of neonates admitted to a Neonatal Intensive Care Unit (NICU) in the Netherlands during a 12 year period confirmed viral infection in about 1% of cases. Enterovirus or parechovirus (EV/PeV) were the most frequent causes (39% of cases), followed by respiratory syncytial virus (RSV) at 29% (Table 118.1). EVs caused the highest mortality rate and serious sequelae [1].
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References
Verboon-Maciolek MA, Krediet TG, Gerards LJ et al (2005) Clinical and epidemiologic characteristics of viral infections in a neonatal intensive care unit during a 12-year period. Pediatr Infect Dis J 24: 901–904
Verboon-Maciolek MA, Krediet TG, Gerards LJ et al (2008) Severe neonatal parechovirus infection and similarity with enterovirus infection. Pediatr Infect Dis J 27: 241–245
Abzug MJ (2004) Presentation, diagnosis, and management of enterovirus infections in neonates. Paediatr Drugs 6: 1–10
Cherry JD (2006) Enterovirus and Parechovirus Infections. In: Remington JS, Klein JO, Wilson CD et al (eds) Infectious diseases of the fetus and newborn infant. Saunders, Philadelphia, pp 783–822
Verboon-Maciolek MA, Groenendaal F, Cowan F et al (2006) White matter damage in neonatal enterovirus meningoencephalitis. Neurology 66: 1267–1269
Rasch G, Schreier E, Kiehl W et al (2001) Worldwide eradication of poliomyelitis. Wien Klin Wochenschr 113: 839–845
Fjaerli HO, Farstad T, Rød G et al (2005) Acute bronchiolitis in infancy as risk factor for wheezing and reduced pulmonary function by seven years in Akershus County, Norway. BMC Pediatr 5: 31
Guerguerian AM, Gauthier M, Lebel MH et al (1999) Ribavirin in ventilated respiratory syncytial virus bronchiolitis. A randomized, placebo-controlled trial. Am J Respir Crit Care Med 160: 829–834
Chávez-Bueno S, Mejías A, Merryman RA et al (2007) Intravenous palivizumab and ribavirin combination for respiratory syncytial virus disease in high-risk pediatric patients. Pediatr Infect Dis J 26: 1089–1093
Simões EA, Carbonell-Estrany X, Fullarton JR et al (2008) A predictive model for respiratory syncytial virus (RSV) hospitalisation of premature infants born at 33-35 weeks of gestational age, based on data from the Spanish FLIP Study. Respir Res 9: 7810
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Manzoni, P., d’Oulx, E.A., Tovo, PA. (2012). Neonatal Viral Infections: Enteroviruses, and Respiratory Syncytial Virus. In: Buonocore, G., Bracci, R., Weindling, M. (eds) Neonatology. Springer, Milano. https://doi.org/10.1007/978-88-470-1405-3_118
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DOI: https://doi.org/10.1007/978-88-470-1405-3_118
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