Neonatology pp 770-774 | Cite as

Coagulation Disorders: Inflammation and Thrombosis

  • Jennifer L. Armstrong-Wells
  • Marilyn J. Manco-Johnson


With a fifteen-fold increase in rate compared with infants and children, thrombosis is an important problem in the neonate. Most neonatal thromboses are diagnosed in the intensive care nursery in association with myriad underlying disorders, many of which are inflammatory. Clinically, most cases of neonatal thrombosis occur in two discrete populations: spontaneous perinatal events (primarily stroke and renal vein thrombosis) or catheter-related thrombosis related to neonatal intensive supportive care. The relationship of inflammation to these two categories of thrombosis is currently unknown.


Newborn Infant Renal Vein Thrombosis Placental Insufficiency Perinatal Stroke Intensive Care Nursery 
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Copyright information

© Springer-Verlag Italia 2012

Authors and Affiliations

  • Jennifer L. Armstrong-Wells
  • Marilyn J. Manco-Johnson
    • 1
  1. 1.Department of Pediatrics, Section of Hematology/Oncology/Bone Marrow Transplant, and Hemophilia and Thrombosis Center, University of ColoradoChildren’s Hospital ColoradoAuroraUSA

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