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Metabolic Bone Disease

  • Paul J. Ryan

Abstract

Metabolic bone disease encompasses a number of disorders that typically show involvement of the entire skeleton. They are mostly associated with increased bone turnover and increased uptake of radiolabeled diphosphonate. The increased uptake produces heightened contrast on bone scan between bone and soft tissues, deceptively giving the appearance of excellent image quality. In more severe cases, there may be characteristic patterns of abnormality, including one or more of the following metabolic features [1]:
  1. 1.

    Increased tracer uptake in the long bones

     
  2. 2.

    Increased tracer uptake in the axial skeleton

     
  3. 3.

    Increased uptake in the periarticular areas

     
  4. 4.

    Faint or almost absent kidney images

     
  5. 5.

    Prominent calvaria and mandibule

     
  6. 6.

    Beading of the costochondral junctions

     
  7. 7.

    “Tie” sternum

     

Keywords

Toxicity Osteoporosis Cage Fluorine Dition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2009

Authors and Affiliations

  • Paul J. Ryan
    • 1
  1. 1.Department of Nuclear MedicineMedway Maritime HospitalGillinghamUK

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