Abstract
Familial adenomatous polyposis is a hereditary autosomal dominant disease; the APC gene is responsible. The multifactorial regulation of this gene expresses many different clinical features and almost all patients present with polyps in the foregut, so gastroenterologists and surgeons should carefully check patient’ upper gastrointestinal tract as well. The diagnosis of polyps in the stomach and, mostly, in the duodenum is of crucial relevance due the high risk of developing a cancer. A better understanding of the natural history of the disease, together with recent developments in operative endoscopy and surgery, make it possible to offer these patients better interdisciplinary management.
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Comberlato, M., Martin, F. (2009). Diagnosis and Treatment of Upper Gastrointestinal Polyps in Polyposis. In: Delaini, G.G., Skřička, T., Colucci, G. (eds) Intestinal Polyps and Polyposis. Springer, Milano. https://doi.org/10.1007/978-88-470-1124-3_11
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DOI: https://doi.org/10.1007/978-88-470-1124-3_11
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-1123-6
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