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Poloxamine Hydrogels: from low Cell Adhesion Substrates to Matrices with Improved Cytocompatibility for Tissue Engineering Applications

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Abstract

Polyethylene glycol based hydrogels are being considered as tissue substitutes. Here we describe the preparation of synthetic collagen-mimetic material that are stirrer than collagen but that like collagen allow for both cell encapsulation and cell growth on the surface. These materials are poloxamine based hydrogels with and without collagen; poloxamine is a four-arm PEO-PPO block copolymer derivative, Tetronic™ 107.

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  1. Institute of Biomaterials and Biomedia Engineering, University of Toronto, Canada

    Alejandro Sosnik, Omar F. Khan, Mark Butler & Michael V. Sefton

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  1. Alejandro Sosnik
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  2. Omar F. Khan
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Sosnik, A., Khan, O.F., Butler, M., Sefton, M.V. (2009). Poloxamine Hydrogels: from low Cell Adhesion Substrates to Matrices with Improved Cytocompatibility for Tissue Engineering Applications. In: Hydrogels. Springer, Milano. https://doi.org/10.1007/978-88-470-1104-5_8

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