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Hydrogels pp 43-51 | Cite as

Hydrogels for Healing

  • Buddy D. Ratner
  • Sarah Atzet

Abstract

Hydrogels are widely used in medicine and offer advantages in many implant situations. However, the body responds to them as with any other material — by walling them off in a foreign body capsule. We show here that by making hydrogels with uniform, interconnected spherical pores of about 35 microns, the healing reaction can be shifted to one of vascularization and little fibrosis. We have also developed a biodegradable form of poly(2-hydroxyethyl methacrylate) that can be used to fabricate these pro-healing, spherically pored materials.

Keywords

Atomic Radical Transfer Polymerization Foreign Body Reaction Biomed Mater PMMA Microsphere Biodegradable Hydrogel 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia, Milan 2009

Authors and Affiliations

  • Buddy D. Ratner
    • 1
  • Sarah Atzet
    • 1
  1. 1.University of Washington Engineered Biomaterials (UWEB) Departments of Bioengineering and Chemical EngineeringUniversity of WashingtonUSA

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