Abstract
Multiple factors are associated with an increased risk of developing breast cancer, including age, family history, exposure to reproductive hormones, dietary factors, benign breast diseases, and environmental factors. Recently, increasing interest has been devoted to the interaction between environmental and genetic factors. Family history has been recognized as an important risk factor for developing breast cancer. Individuals with a first-degree family member affected with breast cancer have a relative risk of 2.1 (95% CI = 2.0–2.2). Moreover, risk varies with the age at which the affected relative was diagnosed, the number of affected and unaffected family members and, finally, the closeness of the relationship.
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Pensabene, M. et al. (2009). The Cancer Spectrum Related to Hereditary and Familial Breast and Ovarian Cancers. In: Multiple Primary Malignancies. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-1095-6_10
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DOI: https://doi.org/10.1007/978-88-470-1095-6_10
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-1094-9
Online ISBN: 978-88-470-1095-6
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