Epidemiology, Classification, Etiopathogenesis, and Diagnosis of Acute Pancreatitis

  • Gianluca Guercioni
  • Walter Siquini
  • Emidio Senati
Part of the Updates in Surgery book series (UPDATESSURG)


In 1925, Moynihan described the dramatic nature of acute pancreatitis as the “most terrible of all calamities that occurs in connection with the abdominal viscera. The suddenness of its onset, the illimitable agony which accompanies it, and the mortality attendant upon it renders it the most formidable of catastrophes” [1]. From mild and self-limiting disease to multiorgan failure and sepsis, acute pancreatitis is a disorder that has numerous causes, an obscure pathogenesis, few effective remedies, and an often unpredictable outcome. The anatomopathological alterations of the pancreatic parenchyma vary from interstitial edema and very limited necrosis of the parenchymal fat to extensive areas of pancreatic necrosis and bleeding.


Acute Pancreatitis Acinar Cell Severe Acute Pancreatitis Pancreatic Necrosis Autoimmune Pancreatitis 
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Copyright information

© Springer-Verlag Italia 2009

Authors and Affiliations

  • Gianluca Guercioni
    • 1
  • Walter Siquini
    • 2
  • Emidio Senati
    • 1
  1. 1.Division of General SurgeryC. e G. Mazzoni County HospitalAscoli PicenoItaly
  2. 2.Department of Surgery, Ospedali Riuniti University HospitalPolytechnic University of MarcheAnconaItaly

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