Orthopedic Surgery in Hemophiliac Patients: a Physiotherapist’s Point of View

  • Kathy Mulder


Hemophilia is an ancient disease, but the ability to perform orthopedic surgery safely on people with hemophilia is a recent development. Prior to the discovery of cryoprecipitate in 1965, death was an almost-guaranteed complication of surgery in a hemophiliac patient. In 1890, in keeping with the current state of surgical knowledge, König opened the knee joints of two patients “to relieve painful swollen joints”. The positive outcome of this was the world’s first published description of hemophilic arthritis. However, both patients died from the ensuing blood loss [1].


Total Knee Replacement Hemophiliac Patient Elective Orthopedic Surgery Ancient Disease Hemophilia Treatment 
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  1. 1.
    König F (1890) Die Gelenkerkrankungen bei Blutern mit besonderer Berücksichtigung der Diagnose, Chirugie I, p 232Google Scholar
  2. 2.
    Brown DL, Hardisty RM, Kosoy MH, Bracken C (1967) Antihaemophilic globulin: preparation by an improved cryoprecipitation method and clinical use. BMJ 2(5544):79–85PubMedCrossRefGoogle Scholar
  3. 3.
    Jordan HH (1967) Hemophilia-rehabilitation and prophylaxis. Proc Rudolf Virchow Med Soc City NY 26:35–38Google Scholar
  4. 4.
    Jordan HH (1967) Conservative orthopaedic approach to rehabilitation of the severely crippled hemophiliac. Wiederherstellungschir Traumatol 9:95–106PubMedGoogle Scholar
  5. 5.
    Jordan HH (1965) Orthopedic aspects of hemophilia. Acta Orthop Belg 31(4):640–647PubMedGoogle Scholar
  6. 6.
    Solimeno LP, Perfetto OS, Pasta G, Santagostino E (2006) Total joint replacement in patients with inhibitors. Haemophilia 12(Suppl 3):113–116PubMedCrossRefGoogle Scholar
  7. 7.
    Rodríguez-Merchán EC, Wiedel JD Jr, Wallny T et al (2004), Elective orthopedic surgery for hemophilia patients with inhibitors: New opportunities. Semin Hematol 41(1 Suppl 1):109–116PubMedCrossRefGoogle Scholar
  8. 8.
    Stephensen D (2005) Rehabilitation of patients with haemophilia after orthopaedic surgery: a case study. Haemophilia 11(Suppl 1):26–29PubMedCrossRefGoogle Scholar
  9. 9.
    Jones CA, Beaupre LA, Johnston DWC, Suarez-Almazor ME (2005) Total joint arthroplasties: current concepts of patient outcomes after surgery. Clin Geriatr Med p 21Google Scholar
  10. 10.
    Sharma L, Sinacore J, Daugherty C et al (1996) Prognostic factors for functional outcome of total knee replacement: a prospective study. J Gerontol A Biol Sci Med Sci 51(4):M152–157PubMedGoogle Scholar
  11. 11.
    Mancuso CA, Sculco TP, Wickiewicz TL et al (2001) Patients’ expectations of knee surgery. J Bone Joint Surg Am 83-A(7):1005–1012PubMedGoogle Scholar
  12. 12.
    Kerr CB (1963) The Fortunes of Haemophiliacs in the Nineteenth Century, Med Hist 7:359–370PubMedGoogle Scholar
  13. 13.
    Boone DC (1976) Comprehensive Management of Hemophilia. F.A. Davis Company, Philadelphia ISBN 0-8036-1000-10009Google Scholar
  14. 14.
    Rodríguez-Merchán EC (2002) Orthopaedic surgery of haemophilia in the 21st century: an overview. Haemophilia 8(3):360–368PubMedCrossRefGoogle Scholar

Copyright information

© Springer 2008

Authors and Affiliations

  • Kathy Mulder
    • 1
  1. 1.Musculoskeletal Committee, World Federation of Hemophilia, and Physiotherapist, Manitoba Bleeding Disorders ProgramHealth Sciences CenterWinnipegCanada

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