Percutaneous Treatment of Hemophilic Cysts using “Fibrin Glue”

  • Federico Fernández-Palazzi
  • Freddy Chakal
  • Rafael Viso


Pseudotumors in hemophilia are a clinical entity rather than a specific pathological injury, described for the first time by Starker in 1918 [1]. De Valderrama and Mathew have defined a pseudotumor as a subperiostic hemorrhage, Steiner and Mejía state that repeated bleeding causes lysis and expansion of the cortex and medulla [2, 3, 4], and Martínez and Vinageras believe pseudotumors are caused by various subperiostic hemorrhages over a period of several months [5]; others think that the bleeding is intra-osseous, subperiosteal, and intramuscular, and that it is a result of a traumatic episode. However, there is not always a cause-effect relationship, since in some cases the period of time between the trauma and the injury is very long, or there simply isn’t any history of trauma. Either way, pressure seems to cause the injury, as Larsen demonstrated by injecting salt solution under the periosteum with a continuous pressure of 180 ml H2O for 12 h [3, 6, 7, 8].


Fibrin Glue Percutaneous Treatment Giant Cell Tumor Factor Viii Activity Compression Bandage 
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Copyright information

© Springer 2008

Authors and Affiliations

  • Federico Fernández-Palazzi
    • 1
  • Freddy Chakal
    • 2
  • Rafael Viso
    • 2
  1. 1.Orthopedic Unit National Hemophilia Treatment CentreMunicipal Blood Bank of CaracasCaracasVenezuela
  2. 2.Department of OrthopedicsMunicipal Blood Bank of CaracasCaracasVenezuela

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