Abstract
Patients with hemorrhagic diatheses such as hemophilia A and B, and von Willebrand syndrome frequently develop spontaneous bleeding, especially in the musculoskeletal system. Although the incidence of joint bleeding has been significantly reduced over the last 30 years through the consistent use of prophylaxis and clotting factor replacement, and the clinical manifestations of this patient population in the area of orthopedics have undergone radical transformation in recent years, these patients are still at risk from joint dysfunction due to bleeding [1]. An ongoing multicenter study involving motion analysis in children with hemophilia aged 3 to 18 years was launched 2 1/2 years ago. Fourtyhundred knee joints have been analyzed to date. The study showed age-dependent kinematic development of the knee joint, with patterns that differed in terms of coordination (treadmill walking) and strength (knee bends). In addition to these age-dependent criteria, another biomechanical criterion pertaining to motion analysis also became apparent which was entirely independent of age: the roll and glide pattern of the knee joints. Whereas a regression coefficient of 0.59 was estimated with reference to age for knee bends, and a value of 0.54 for gait, the age correlation of the score for internal knee joint kinematics was 0.05 [2–6].
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References
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Seuser, A. (2008). Conservative or Surgical Treatment? Motion Analysis Can Help Decide. In: Caviglia, H.A., Solimeno, L.P. (eds) Orthopedic Surgery in Patients with Hemophilia. Springer, Milano. https://doi.org/10.1007/978-88-470-0854-0_3
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DOI: https://doi.org/10.1007/978-88-470-0854-0_3
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