Rifampicin Synoviorthesis of the Ankle Joint
Hemophilia, a hereditary blood clotting disorder, characterized by joint bleeds (either spontaneous or injury-induced), is known to cause arthropathy in affected males. The only preventive treatment available to protect from joint bleeds is replacement of the relevant clotting factor that is deficient. After several bleeding episodes, persistent synovitis with swelling of a joint develops in patients with hemophilia, despite adequate therapy. This condition seems to be inflammatory rather than hemorrhagic. Chronic synovitis persists in moderate and severe hemophilia, despite improved and increased availability of clotting factors . Patients with synovitis are again prone to develop recurrent bleeds and joint damage, which is quite disabling.
KeywordsAnkle Joint Severe Hemophilia Synovial Thickness Chronic Synovitis Transient Synovitis
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