Imaging the Effects of Systemic Metabolic Diseases on the Brain

  • Mauricio Castillo


This short review addresses the most important and common metabolic disorders that result in abnormal neuroimaging studies in clinical practice. In these cases, the patient’s medical history is of the utmost importance, as imaging findings may be relatively nonspecific. This chapter concentrates on disorders that produce somewhat specific brain findings and thus are amenable to diagnosis by the radiologist. Most of these disorders affect the gray matter. Diffuse and focal involvement of the gray matter is generally secondary to ischemia (focal cortical involvement may be seen with seizures) and is not addressed here. Instead, the focus here is on abnormalities involving the subcortical gray matter.


Hepatic Encephalopathy Globus Pallidus Thrombotic Thrombocytopenic Purpura Wilson Disease Central Pontine Myelinolysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Mauricio Castillo
    • 1
  1. 1.Department of RadiologyUniversity of North Carolina at Chapel HillChapel HillUSA

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