Demyelinating Diseases - I

  • Kelly K. Koeller


The oligodendrocyte, predominantly found in the white matter of the brain, is the cell responsible for the production of myelin. As a general rule, demyelinating diseases result from either attacks on this cell or failure of the cell to regenerate under normal conditions. Consequently, a focal or diffuse loss of myelin occurs. Multiple sclerosis (MS) is the prototypical white matter disease. Many other diseases may mimic its appearance on imaging studies. While not an exhaustive list, this review highlights the important imaging manifestations of these demyelinating diseases that allow more specific diagnosis.


Multiple Sclerosis White Matter Progressive Multifocal Leukoencephalopathy Demyelinating Disease Progressive Multifocal Leukoencephalopathy 


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Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Kelly K. Koeller
    • 1
  1. 1.Department of RadiologyMayo ClinicRochesterUSA

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