Advertisement

Brain Tumors

  • Edmond A. Knopp
  • Walter Montanera

Abstract

The designation “brain tumor” is commonly applied to a wide variety of intracranial mass lesions, each distinct in their location, biology, treatment, and prognosis. Since many of these lesions do not arise from brain parenchyma, the more appropriate term would be “intracranial tumors”. Since the category encompasses both neoplasms and non-neoplastic mass lesions, the word “tumor” is used in its broadest sense, indicating a space-occupying mass.

Keywords

Cerebral Blood Volume Arachnoid Cyst Primary Central Nervous System Lymphoma Cerebellopontine Angle Perfusion Magnetic Resonance Imaging 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Suggested Reading

  1. Al-Okaili RN, Krejza J, Wang S et al (2006) Advanced MR imaging techniques in the diagnosis of intraaxial brain tumors in adults. Radiographics. 26Suppl 1:S173–S189PubMedCrossRefGoogle Scholar
  2. Atlas SW, Lavi E, Fisher PG (2002) Intraaxial brain tumors. In: Atlas SW (ed) Magnetic resonance imaging of the brain and spine. Lippincott Williams & Wilkins, Philadelphia, pp 565–693Google Scholar
  3. Atlas SW, Lavi E, Golberg HI (2002) Extraaxial brain tumors. In: Atlas SW (ed) Magnetic resonance imaging of the brain and spine. Lippincott Williams & Wilkins, Philadelphia, pp 695–772Google Scholar
  4. Bode MK, Ruohonen J, Nieminen MT et al (2006) Potential of diffusion imaging in brain tumors: a review. Acta Radiol 47(6):585–594PubMedCrossRefGoogle Scholar
  5. Castillo M, Mukherji SK (2000) Diffusion-weighted imaging in the evaluation of intracranial lesions. Semin Ultrasound CT MR 21:405–416PubMedCrossRefGoogle Scholar
  6. Cha S, Knopp EA, Johnson G et al (2000) Dynamic, contrast-enhanced T2*-weighted MR imaging of recurrent malignant gliomas treated with thalidomide and carboplatin. AJNR Am J Neuroradiol 21:881–890PubMedGoogle Scholar
  7. Cha S, Knopp EA, Johnson G et al (2002) Intracranial mass lesions: dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging. Radiology 223:11–29PubMedCrossRefGoogle Scholar
  8. Chenevert TL, Meyer CR, Moffat BA et al (2002) Diffusion MRI: a new strategy for assessment of cancer therapeutic efficacy. Mol Imaging 1:336–343PubMedCrossRefGoogle Scholar
  9. DeAngelis LM (2001) Brain tumors. N Engl J Med 344:114–123PubMedCrossRefGoogle Scholar
  10. Ding B, Ling HW, Chen KM et al (2006) Comparison of cerebral blood volume and permeability in preoperative grading of intracranial glioma using CT perfusion imaging. Neuroradiology 48(10):773–81PubMedCrossRefGoogle Scholar
  11. Earnest F 4th, Kelly PJ, Scheithauer BW et al (1988) Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy. Radiology 166:823–827PubMedGoogle Scholar
  12. Ellika SK, Jain R, Patel SC et al (2007) Role of perfusion CT in glioma grading and comparison with conventional MR imaging features. AJNR Am J Neuroradiol 28(10):1981–1987PubMedCrossRefGoogle Scholar
  13. Fine HA (1995) Novel biologic therapies for malignant gliomas. Antiangiogenesis, immunotherapy, and gene therapy. Neurol Clin 13:827–846PubMedGoogle Scholar
  14. Fitzpatrick M, Tartaglino LM, Hollander MD et al (1999) Imaging of sellar and parasellar pathology. Radiol Clin North Am 37:101–121PubMedCrossRefGoogle Scholar
  15. Grossman RI, Yousem DM (2003) Neoplasms of the Brain. In: Thrall JH ed. Neuroradiology: the requisites. Mosby-Elsevier, Philadelphia, pp 97–172Google Scholar
  16. Hollingworth W, Medina LS, Lenkinski RE et al (2006) A systematic literature review of magnetic resonance spectroscopy for the characterization of brain tumors. AJNR Am J Neuroradiol 27(7):1404–1411PubMedGoogle Scholar
  17. Kleinman G, Zagzag D, Miller D (1994) Diagnostic use of immunohistochemistry in neuropathology. Neurosurg Clin N Am 5:97–126PubMedGoogle Scholar
  18. Knopp EA, Cha S, Johnson G et al (1999) Dynamic contrast-enhanced T2*-weighted MR imaging of glial neoplasms. Radiology 211:791–798PubMedGoogle Scholar
  19. Koeller KK, Smirniotopoulos JG, Jones RV (1997) Primary central nervous system lymphoma: radiologic-pathologic correlation. Radiographics 17:1497–1526PubMedGoogle Scholar
  20. Lassman AB, DeAngelis LM (2003) Brain metastases. Neurol Clin 21:1–23PubMedCrossRefGoogle Scholar
  21. Law M, Cha S, Knopp EA et al (2002) High-grade gliomas and solitary metastases: differentiation using perfusion MR imaging and proton spectroscopic MR imaging. Radiology 222:715–721PubMedCrossRefGoogle Scholar
  22. Law M, Yang S, Wang H et al (2003) Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging. AJNR Am J Neuroradiol 24(10):1989–1998PubMedGoogle Scholar
  23. Le Bihan D, Douek P, Argyropoulou M et al (1993) Diffusion and perfusion magnetic resonance imaging in brain tumors. Top Magn Reson Imaging 5:25–31PubMedCrossRefGoogle Scholar
  24. Louis DN, Ohgaki H, Wiestler OD (eds) (2007) WHO classification of tumours of the central nervous system, 4th edn. IARC, LyonGoogle Scholar
  25. Luh GY, Bird CR (1999) Imaging of brain tumors in the pediatric population. Neuroimaging Clin N Am 9:691–716PubMedGoogle Scholar
  26. Maiuri F, Iaconetta G, de Divitiis O et al (1999) Intracranial meningiomas: correlations between MR imaging and histology. Eur J Radiol 31:69–75PubMedCrossRefGoogle Scholar
  27. Nelson SJ, McKnight TR, Henry RG (2002) Characterization of untreated gliomas by magnetic resonance spectroscopic imaging. Neuroimaging Clin N Am 12:599–613PubMedCrossRefGoogle Scholar
  28. Norfray JF, Darling C, Byrd S et al (1999) Short TE proton MRS and neurofibromatosis type 1 intracranial lesions. J Comput Assist Tomogr 23(6):994–1003PubMedCrossRefGoogle Scholar
  29. Poussaint TY (2001) Magnetic resonance imaging of pediatric brain tumors: state of the art. Top Magn Reson Imaging 12:411–433PubMedCrossRefGoogle Scholar
  30. Provenzale JM, Mukundan S, Barboriak DP (2006) Diffusion-weighted and perfusion MR imaging for brain tumor characterization and assessment of treatment response. Radiology 239(3):632–649PubMedCrossRefGoogle Scholar
  31. Schiffer D (1991) Pathology of brain tumors and its clinicobiological correlates. Dev Oncol 66:3–9Google Scholar
  32. Schiffer D (2000) Glioma malignancy and its biological and histological correlates. J Neurosurg Sci 34:163–165Google Scholar
  33. Sheporaitis LA, Osborn AG, Smirniotopoulos JG et al (1992) Intracranial meningioma. AJNR Am J Neuroradiol 13:29–37PubMedGoogle Scholar
  34. Sibtain NA, Howe FA, Saunders DE (2007) The clinical value of proton magnetic resonance spectroscopy in adult brain tumours. Clin Radiol 62(2):109–119PubMedCrossRefGoogle Scholar
  35. Young RJ, Knopp EA (2006) Brain MRI: tumor evaluation. J Magn Reson Imaging 24(4):709–724PubMedCrossRefGoogle Scholar
  36. Zamani AA (2000) Cerebellopontine angle tumors: role of magnetic resonance imaging. Top Magn Reson Imaging 11:98–107PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Edmond A. Knopp
    • 1
  • Walter Montanera
    • 2
  1. 1.Magnetic Resonance Imaging DepartmentNew York University School of MedicineNew YorkUSA
  2. 2.Department of Medical Imaging, St. Michael’s HospitalUniversity of TorontoTorontoCanada

Personalised recommendations